I have had the worst time setting up a single, integrated workflow that works for me. I've flitted endlessly between text files, Entourage, Mail.app, vim, online RSS-based calendars, all-in-one apps, paper planners, Moleskines, index cards, and more in search of the right combination. Each tool and habit has its benefits, to be sure, but I never seem to land on a really satisfying set of apps and practices that feels like it has exactly the right "flow" to it. Most corrosively, I often (really often) blow tons of time ramping up to some new bauble only to ultimately discover it lacks some critical piece (export, reminders, etc. etc.). Bad habits for someone who ostensibly wants his work life to be more productive and waste-free.Link
Of course, I can write some of the time and effort down to "research" and the fact that part of my work involves learning about new productivity widgets, but I can't avoid the fact that I still don't have a method of handling all my information (and actual work) in a way that I find satisfying and intuitive. Plus I have to admit to some terrible habits surrounding my ongoing search for "The Perfect System(TM)."
I write books. My latest is a YA science fiction novel called Homeland (it's the sequel to Little Brother). More books: Rapture of the Nerds (a novel, with Charlie Stross); With a Little Help (short stories); and The Great Big Beautiful Tomorrow (novella and nonfic). I speak all over the place and I tweet and tumble, too.