Why die?

British computer scientist Aubrey de Grey is convinced that human beings can live forever. So he taught himself natural science to figure out the scientific steps he believes must be taken to make that happen. Sherwin Nulan, author of How We Die, has written a long, deep profile of de Grey in the new issue of Technology Review.

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"As he surveyed the literature, de Grey reached the conclusion that there are seven distinct ingredients in the aging process, and that emerging understanding of molecular biology shows promise of one day providing appropriate technologies by which each of them might be manipulated—"perturbed," in the jargon of biologists. He bases his certainty that there are only seven such factors on the fact that no new factor has been discovered in some twenty years, despite the flourishing state of research in the field known as biogeron­tology, the science of aging; his certainty that he is the man to lead the crusade for endless life is based on his conception that the qualification needed to accomplish it is the mindset he brings to the problem: the goal-driven orientation of an engineer rather than the curiosity-driven orientation of the basic scientists who have made and will continue to make the laboratory discoveries that he intends to employ. He sees himself as the applied scientist who will bring the benisons of molecular bi­ology to practical use. In the analogous terminology often used by historians of medicine, he is the clinician who will bring the laboratory to the bedside."

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