The new Honda Civic UK commercial is based around a chorus who create all of the sound effects with their mouths. It's amazing. Hit the link to get to the Honda Civic page, skip the Flash intro, and then hit the "Watch" button. Link to Honda's site, Link directly to a mirror of the video (Thanks, Eric Paulos!)
UPDATE: Thanks to Amy's Robot, here's the video as an iPod-compatible Mpeg4. Link
David Pescovitz is Boing Boing's co-editor/managing partner. He's also a research director at Institute for the Future. On Instagram, he's @pesco.