I just found out about a new version that has every issue of MAD from 1952-2006 on one DVD. That's over 600 issues (17,500 pages), plus a bunch of special features such as interviews and some animation. It also runs on Mac machines, and the pages are in PDF format, which is great for printing and viewing on handheld devices (I hope).
I can't wait to get my copy! Link
Mark Frauenfelder is the founder of Boing Boing and the editor-in-chief of MAKE and Cool Tools. Twitter: @frauenfelder. His new book is Maker Dad: Lunch Box Guitars, Antigravity Jars, and 22 Other Incredibly Cool Father-Daughter DIY Projects