Eric sez, "Australian scientists developed a cheap blood test for African sleeping sickness and gave it away under a Creative Commons license."
Zablon Njiru and Andrew Thompson of Murdoch University led a team that developed the elegantly simple way to check for trypanosomes -- protozoan parasites that are sometimes carried by tsetse flies.
To catch an infection in the earliest stages, when it is most treatable, technicians must look for a very small number of parasites in a sea of body fluids. That is not an easy thing to do, but there is a trick to make it easier: By mixing the liquid sample with a cocktail of molecules that can copy trypanosome DNA, they can make the serum resistance associated gene, a signpost of the disease, stand out -- transforming each test into a manageable task.
Instead of using the polymerase chain reaction, which amplifies the microbe DNA with the aid of an expensive instrument called a thermocycler, the researchers employed another gene multiplying technique called loop-mediated isothermal amplification. It requires little more than a warm water bath and a few chemicals. After that procedure, which takes less than a half hour, the scientists can simply add some SYBR green dye and watch the brew change color if it contains a boatload of duplicated genetic material from the pathogen.
Randall “XKCD” Munroe’s Thing Explainer: Complicated Stuff in Simple Words arrives in stores today: it combines technical diagrams and wordplay in pure display of everything that makes XKCD brilliant and wonderful in every way.
Bats and skateboarders have something special in common. They both use inertia to land their tricks which, in a bat’s case, means landing upside down.
Don’t miss this amazing film.
Carrying this EDC card is like slinging around a handheld toolbox wherever you go. Its minimal design is small enough to fit in your wallet’s billfold, and it’s TSA-compliant so you’ll never leave it behind. It’s got hex wrenches, metric and imperial rulers, flathead and Phillip’s screwdrivers, and a bottle opener so that you’re ready […]
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