No, we're not talking shock therapy. Researchers at the University of Toronto installed deep brain stimulating electrodes in 20 patients with severe depression who weren't helped by other means. Twelve of those individuals saw big improvement and seven experiences a "full remission." The electrodes stimulated a region of the brain called the subcallosal cingulated gyrus. Other centers around the world are running similar studies but zapping different parts of the brain.
“In the meantime we need to know why some of the patients don’t respond at all,” says (researcher Helen) Mayberg. “Are we missing the target, or are there different subtypes of the disease?” Her team is now trying to find out how to identify those who will respond to DBS, and those who won’t. “Brain surgery is not like getting your nails done, so it is important to try to find out who will benefit..."
Neurologists think that the therapy works by activating or damping down particular brain circuits. At the moment, no-one knows which of the targets within these circuits will eventually prove to be the most optimal...
The centres are also investigating the value of DBS in other psychiatric disturbances, such as obsessive compulsive disorder and addiction.
Where are our petabyte drives? Brian Hayes takes us through the reasons storage is “stuck” in the low terabytes. The tl;dr is that we got such exceptional capacity growth in the late 90s and early 00s we don’t need much more right now, so the focus since then has been on SSDs, networking, interfaces, etc, […]
Amélie Lamont, a former staffer at website-hosting startup Squarespace, writes that she often found herself disregarded and disrespected by her colleagues. One comment in particular, though, set her reeling — and came to exemplify her experiences there.
In this episode of the Flash Forward podcast we travel to a future where humans have decided to eradicate the most dangerous animal on the planet: mosquitos. How would we do it? Is it even possible? And what are the consequences? Flash Forward: RSS | iTunes | Twitter | Facebook | Web | Patreon We […]
Almost everyone has their smartphone in a case of one kind or another. Beyond simple protection, finding a case that can charge your phone on its own, but doesn’t feel like it’s also adding a couple pounds to the phone’s weight is the tricky part. Billed as the world’s thinnest battery case, the ThinCharge iPhone […]
You never know when new projects, ideas or opportunities can drop into your lap at a moment’s notice. That may require you to learn a new programming language like Python. Or maybe you need a primer on 3D game development. Or you might realize you could use a serious brush-up on iOS mobile creation.Point is, […]
Isn’t it about time to stretch what your Mac can do? I mean, you’ve got plenty of great programs now…but don’t you think you could use some new tools to get your creative, analytical and organizational juices really flowing? It’s spring, so we cleaned up a whole bunch of super-cool apps lying around and packaged […]