Lisa from Sociological Images came across this grim animated commercial from the 1950s for Jell-O. It shows a haggard woman on a treadmill being assaulted by symbols of her daily grind. The look on her face is one of pure despair. The female narrator seems to be taunting her. The plaintive harmonica tune that's playing is both sad and intentionally insipid. At the woman's blackest moment, she gets covered up by a black scrawl. (I wonder if UPA designed the commercial?)
All is cured, of course, once she buys a box of Jello-O instant pudding.