CCrawford sez, "Michelle Khine couldn't afford the $100,000 fabrication gear to make micro-fluidic chips needed for chip-based diagnostic tests. She turned to Shrinky-Dinks and found a new way to solve the problem."
To test her idea, she whipped up a channel design in AutoCAD, printed it out on Shrinky Dink material using a laser printer, and stuck the result in a toaster oven. As the plastic shrank, the ink particles on its surface clumped together, forming tiny ridges. That was exactly the effect Khine wanted. When she poured a flexible polymer known as PDMS onto the surface of the cooled Shrinky Dink, the ink ridges created tiny channels in the surface of the polymer as it hardened. She pulled the PDMS away from the Shrinky Dink mold, and voilà: a finished microfluidic device that cost less than a fast-food meal.
Khine began using the chips in her experiments, but she didn't view her toaster-oven hack as a breakthrough right away. "I thought it would be something to hold me over until we got the proper equipment in place," she says. But when she published a short paper about her technique, she was floored by the response she got from scientists all over the world. "I had no idea people were going to be so interested," Khine says.
NASA today announced that astronomers studying data from NASA’s Great Observatories have found the best evidence yet for “cosmic seeds in the early universe that should grow into supermassive black holes.”
Could you recover a murder victim’s last sight of their killer by extracting it from the retina? Little more than a century ago, forensic scientists thought it might be possible. After all, in 1877 physiologist Wilhelm Friedrich Kühne was able to develop a simple image from an albino rabbit’s dissected eyeball. (Above, the two images […]
Backed by huge donations from vitamin companies, the American Association of Naturopathic Physicians is pushing to get naturopathic medicine recognized and regulated in all 50 US states, paving the way to receiving public funds in the form of Medicare reimbursements.
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