A transatlantic team of scientists have discovered a secondary sensory system, independent of the well-understood nervous system, hidden in the skin. These may be at the root of inexplicable chronic pain syndromes like fibromyalgia.
"It's almost like hearing the subtle sound of a single instrument in the midst of a symphony," said senior author Frank Rice, PhD, a Neuroscience Professor at Albany Medical College (AMC), who is a leading authority on the nerve supply to the skin. "It is only when we shift focus away from the nerve endings associated with normal skin sensation that we can appreciate the sensation hidden in the background."
Hidden Sensory System Discovered in the Skin
The research team discovered this hidden sensory system by studying two unique patients who were diagnosed with a previously unknown abnormality by lead author David Bowsher, M.D., Honorary Senior Research Fellow at the University of Liverpool's Pain Research Institute. These patients had an extremely rare condition called congenital insensitivity to pain, meaning that they were born with very little ability to feel pain. Other rare individuals with this condition have excessively dry skin, often mutilate themselves accidentally and usually have severe mental handicaps...
The answer appeared to be in the presence of sensory nerve endings on the small blood vessels and sweat glands embedded in the skin. "For many years, my colleagues and I have detected different types of nerve endings on tiny blood vessels and sweat glands, which we assumed were simply regulating blood flow and sweating. We didn't think they could contribute to conscious sensation. However, while all the other sensory endings were missing in this unusual skin, the blood vessels and sweat glands still had the normal types of nerve endings. Apparently, these unique individuals are able to 'feel things' through these remaining nerve endings," said Dr. Rice. "What we learned from these unusual individuals is that there's another level of sensory feedback that can give us conscious tactile information. Problems with these nerve endings may contribute to mysterious pain conditions such as migraine headaches and fibromyalgia, the sources of which are still unknown, making them very difficult to treat."
(Image: Nothing But Skin, a Creative Commons Attribution photo from kevindooley's photostream)
More than 800 American energy and Earth science researchers have signed a letter to Donald Trump outlining six steps they’re urging him to take to address human-caused climate change to protect “America’s economy, national security, and public health and safety.” The letter is accompanied by a public change.org petition to “Tell Trump To #ActOnClimate.” Here […]
James Delingpole is an invective-hurling anti-climate science columnist who has candidly admitted that he doesn’t bother to read scientific papers, calling himself a “an interpreter of interpretations.”
Kratom (previously) is a widely used herb that has been very effective in treating opioid withdrawal and other chronic, hard-to-treat conditions — it also became very controversial this year because the DEA decided, without evidence, to class it as a dangerous drug, and then changed its mind (unprecedented!) after a mass-scale petition that included interventions […]
Holiday shopping is in full swing, and the Striiv Touch is one of the best gift ideas I’ve landed on. Its simple design works for females and males, and its wide range of features makes it suitable for even the non-fitness enthusiasts in your life.Unlike traditional fitness trackers, the Striiv Touch also acts as a smartwatch. It […]
The Pocket Tripod PRO had massive Kickstarter success in 2013, raising almost $85,000 in a single month. But this isn’t just another case of pre-release product hype. This ingenious little device folds out from a credit-card-shaped plastic slab into a sturdy stand with a surprisingly wide range of motion. In portrait orientation, your phone slides […]
Loot Crate is a totally different kind of subscription service that mails subscribers monthly boxes filled with curated geek, pop culture, and gamer paraphernalia. Its cult following awaits a box every month filled with everything from bobble heads to T-shirts to special edition collectibles. But nothing gets Loot Crate fans as excited as the limited […]