A Norwegian study published in the Journal of the American Medical Association showed that glucosamine has no effect on relieving lower back pain. Six million Americans take glucosamine supplements.
For six months, he and his colleagues gave 250 adults with chronic lower back pain and degenerative osteoarthritis either 2,500 mg daily of glucosamine sulfate or a placebo. At the six-month and one-year marks, there weren't any significant differences among patients in the two groups. Both groups did seem to be helped by the placebo effect, which is common in pain patients, in which people apparently feel better simply because they are receiving treatment.Glucosamine No Remedy for Lower Back Pain, Says Study (via Consumerist)