Laboratory mice are not the same creatures you'll find living in your wall or a farm field. Instead, they are highly specialized. Whether born of high-tech genetic manipulation or good, old-fashioned selective breeding, each type of mouse—and there are thousands in the catalogs—is designed to test specific types of questions. Use the wrong mouse, and your data will be worthless. Or, at least, your conclusions will be incorrect.
That's what happened recently, when the authors of a 2006 paper in the Journal of Immunology retracted their work after belatedly realizing that it was based on studies done with the wrong mouse. They'd meant to buy a mouse that lacked a specific gene. Instead, thanks to a simple typo, they'd ended up with mice that lacked that gene—and a key chemical receptor in its cells, which changed the outcome of the research.
I've written a little about the strange world of laboratory mice, both here, and in mental_floss. Want more? There's a Wired story by Gary Wolfe that will interest you, as well.
(Via Alexandra Witze)
After years of speculation and wrangling over his remains, Kennewick Man turns out to be closely related to contemporary, local Native Americans after all. Discovered near Kennewick, Wash., in 1996, the skeleton ended up in a tug of war between tribes in the pacific northwest who wanted to bury the remains, and scientists who wanted […]
Our solar system is awesome.
The European Organization for Nuclear Research, or CERN, has been releasing portions of its research to the public for years. This week’s massive 300 terabyte dump of Large Hadron Collider (LHC) data is the biggest yet by a long shot — and it’s all out there, open source, free for the exploration.
Isn’t it about time to stretch what your Mac can do? I mean, you’ve got plenty of great programs now…but don’t you think you could use some new tools to get your creative, analytical and organizational juices really flowing? It’s spring, so we cleaned up a whole bunch of super-cool apps lying around and packaged […]
In the world of app development, there’s no greater arena to find success than with Android users. About 80% of the smartphones in use today worldwide operate on the Android operating system, so if you build a great app that Android users love, you’re an international rock star. You’ll be able to make sure your […]
Unless you’re a programmer or webmaster, the term SQL probably doesn’t mean much to you. But for those looking to understand more about how and why the web works the way that it does, know this – SQL and its process of managing and presenting large data sets is everywhere…and it’s the most in-demand programming […]