Laboratory mice are not the same creatures you'll find living in your wall or a farm field. Instead, they are highly specialized. Whether born of high-tech genetic manipulation or good, old-fashioned selective breeding, each type of mouse—and there are thousands in the catalogs—is designed to test specific types of questions. Use the wrong mouse, and your data will be worthless. Or, at least, your conclusions will be incorrect.
That's what happened recently, when the authors of a 2006 paper in the Journal of Immunology retracted their work after belatedly realizing that it was based on studies done with the wrong mouse. They'd meant to buy a mouse that lacked a specific gene. Instead, thanks to a simple typo, they'd ended up with mice that lacked that gene—and a key chemical receptor in its cells, which changed the outcome of the research.
I've written a little about the strange world of laboratory mice, both here, and in mental_floss. Want more? There's a Wired story by Gary Wolfe that will interest you, as well.
(Via Alexandra Witze)
The PocketLab is billed as a “Swiss Army Knife of science.” Launched via Kickstarter, the small device contains numerous sensors to measure acceleration, force, angular velocity, magnetic field, pressure, altitude, and temperature and send that data to smartphones or laptops. According to inventor Clifton Roozeboom, it’s a tool for students and citizen scientists who can’t […]
In the 2015 Sense About Science lecture (MP3), Tracey Brown discusses the worst casualty of politicization of science, from fluoride to climate change — the truth.
A booming biotech business in South Korea has new customers in America, because everyone wants to clone their dog.
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