Laboratory mice are not the same creatures you'll find living in your wall or a farm field. Instead, they are highly specialized. Whether born of high-tech genetic manipulation or good, old-fashioned selective breeding, each type of mouse—and there are thousands in the catalogs—is designed to test specific types of questions. Use the wrong mouse, and your data will be worthless. Or, at least, your conclusions will be incorrect.
That's what happened recently, when the authors of a 2006 paper in the Journal of Immunology retracted their work after belatedly realizing that it was based on studies done with the wrong mouse. They'd meant to buy a mouse that lacked a specific gene. Instead, thanks to a simple typo, they'd ended up with mice that lacked that gene—and a key chemical receptor in its cells, which changed the outcome of the research.
I've written a little about the strange world of laboratory mice, both here, and in mental_floss. Want more? There's a Wired story by Gary Wolfe that will interest you, as well.
(Via Alexandra Witze)
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Having to pack and drag your stuff through security can put quite the damper on your vacation plans. Thankfully, we’ve got your back with one way to make traveling more painless: the Jumper Overnighter Travel Bag.This compact bag is so lightweight that you can effortlessly carry it, and fit it into any overhead compartment. But just […]
Learning is a 24/7/365 proposition, and it never ends. And if you’re truly serious about leveling up your skill sets and career prospects, get a subscription to Stone River Academy’s massive course collection. This offer normally is worth over $1,400, but is now available for just $89 in the Boing Boing Store.A respected name in information technology […]
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