Laboratory mice are not the same creatures you'll find living in your wall or a farm field. Instead, they are highly specialized. Whether born of high-tech genetic manipulation or good, old-fashioned selective breeding, each type of mouse—and there are thousands in the catalogs—is designed to test specific types of questions. Use the wrong mouse, and your data will be worthless. Or, at least, your conclusions will be incorrect.
That's what happened recently, when the authors of a 2006 paper in the Journal of Immunology retracted their work after belatedly realizing that it was based on studies done with the wrong mouse. They'd meant to buy a mouse that lacked a specific gene. Instead, thanks to a simple typo, they'd ended up with mice that lacked that gene—and a key chemical receptor in its cells, which changed the outcome of the research.
I've written a little about the strange world of laboratory mice, both here, and in mental_floss. Want more? There's a Wired story by Gary Wolfe that will interest you, as well.
(Via Alexandra Witze)
Archaeologists excavating a Hittite city on the border of Turkey and Syria found a broken jug that, upon restoration, revealed a smiley face. At 3,700-years-old, it could be the oldest smiley face drawing ever found. From Smithsonian: According to Zuhal Uzundere Kocalar at Turkey’s state-run news service, the Anadolu Agency, the researchers did not notice […]
On August 3 in celebration of the 40th anniversary month of the Voyager interstellar mission, please join me at San Francisco’s Exploratorium to experience the Voyager Golden Record with two of the brilliant minds behind it — SETI pioneer Frank Drake and science writer Timothy Ferris. In August and September 1977, NASA launched two spacecraft, […]
The Chinese government’s wish-list for AI researchers is pretty ambitious: “Breakthroughs should be made in basic theories of AI, such as big data intelligence, multimedia aware computing, human-machine hybrid intelligence, swarm intelligence and automated decision-making.”
The TREBLAB X11 Earphones are versatile, offer great sound, and are currently $32.99 in the Boing Boing Store.These Bluetooth earbuds are a great workout companion. They’re totally sweat proof and their ear-fins keep them snugly in place during high activity — something that Apple’s AirPods can only do if you were blessed with precisely the […]
Whether you’re a seasoned entertainment industry veteran or a student working on your first spec script, having the right tool for the job will make a huge difference in your focus and productivity.Final Draft 10 is far and away the world’s best screenwriting software, used extensively by professional film and TV writers at top production […]
Web content creators who don’t have a solid SEO strategy should take note of Webtexttool. It’s a service that pulls in anonymous data from their entire user base to offer crowdsourced guidance that increases your search page ranks. By analyzing prior user successes, it helps you better gauge how your posts will perform at a […]