Laboratory mice are not the same creatures you'll find living in your wall or a farm field. Instead, they are highly specialized. Whether born of high-tech genetic manipulation or good, old-fashioned selective breeding, each type of mouse—and there are thousands in the catalogs—is designed to test specific types of questions. Use the wrong mouse, and your data will be worthless. Or, at least, your conclusions will be incorrect.
That's what happened recently, when the authors of a 2006 paper in the Journal of Immunology retracted their work after belatedly realizing that it was based on studies done with the wrong mouse. They'd meant to buy a mouse that lacked a specific gene. Instead, thanks to a simple typo, they'd ended up with mice that lacked that gene—and a key chemical receptor in its cells, which changed the outcome of the research.
I've written a little about the strange world of laboratory mice, both here, and in mental_floss. Want more? There's a Wired story by Gary Wolfe that will interest you, as well.
(Via Alexandra Witze)
University of Zurich researchers used transcranial magnetic stimulation, a noninvasive method of inhibiting activity in parts of the brain, to “turn off” people’s ability to control their impulses. They focused on the temporoparietal junction, an area of the brain thought to play an important role in moral decisions, empathy, and other social interactions. They hope […]
Are you jonesing for a dose of optimism and possibility? In the mood to contemplate the cosmos? Want to experience a musical message for extraterrestrials the way it was meant to be played? The Voyager Golden Record: 40th Anniversary Edition, a project I launched with Timothy Daly and Lawrence Azerrad, is a lavish vinyl box […]
In Rich do not rise early: spatio-temporal patterns in the mobility networks of different socio-economic classes, a group of transportation engineers analyze an open data-set about the commutes of people in the Colombian cities of Medellín and Manizales, concluding that the rich and the poor commute the furthest distances, but that the rich have much […]
Nothing is more frustrating than needing to edit or sign a PDF and not having access to the original document. That’s why PDFpenPRO is a must-have app in our books.With this extremely useful app, you can merge, markup, and create PDF documents without ever having to convert your PDFs into word processor file formats. Type directly onto […]
From self-driving cars to stock market predicting software to the recommendations you get on Amazon and Netflix, machine learning is at the core of modern technology. You could find yourself building technology that is literally changing the world with the skills you’ll learn in The Complete Machine Learning Bundle. This bundle of 10 courses includes 406 lessons that will teach […]
This Python Mega Course will help you learn to code by teaching you to build 10 real-world apps that each highlight a unique use of Python.Job prospects for coders are still growing steadily—and with Python being one of the most popular coding languages out there today, it’s important for job seekers to demonstrate a widespread understanding of the […]