(photo by Curecat/Wikimedia Commons)
Turn off your mind, relax, and float downstream, indeed. A new scientific study suggests that psilocybin -- the psychedelic drug found in magic mushrooms -- doesn't "turn on" parts of your brain but rather restricts blood flow and connections between the regions of the brain tied to perception and cognition. Imperial College London psychopharmacology researcher Robin Carhart-Harris presented the results of this study, in which 30 volunteers were injected with psilocybin and underwent brain scans, at last week's Breaking Convention conference on psychedelic consciousness. Interestingly, the data helps support psilocybin's potential use to treat depression. From New Scientist:
Less blood flow was seen in the brain regions known as the thalamus, the posterior cingulate and the medial prefrontal cortex. "Seeing a decrease was surprising. We thought profound experience equalled more activity, but this formula is clearly too simplistic," says Carhart-Harris. "We didn't see an increase in any regions," he says.
Decreases in connectivity were also observed, such as between the hippocampus and the posterior cingulate and medial prefrontal cortex.
"Under psilocybin you see a relative decrease in 'talk' between the hippocampus and these cortical hub regions," says Carhart-Harris. "Changes in function in the posterior cingulate in particular are associated with changes in consciousness."
Psilocybin has a similar chemical structure to serotonin – a hormone involved in regulating mood – and therefore binds to serotonin receptors on nerve cells in the brain. The drug may have therapeutic potential because the serotonin system in nerves is also a target for existing antidepressants.
"Psychedelic drug cuts brain blood flow and connections
" (Thanks, Jody Radzik!)
Texas State University’s Body Farm (AKA Forensic Anthropology Center at Texas State University or FACTS) is a 45-year-old facility where the corpses of medical body donors are left to decompose so that researchers can observe the rate at which human remains are consumed by the elements, scavengers and microbes, allowing them to accurately date the […]
A better understanding how a sperm swims its way toward an egg could help inform new treatments for male infertility. Researchers from the University of York have now come up with a mathematical formula to model how large numbers of moving sperm interact with fluid they’re swimming through. From the University: By analysing the head […]
Dr Gale Ridge is a public entomologist at the Connecticut Agricultural Experiment Station, where an average of 23 people a day call, write or visit; an increasing proportion of them aren’t inquiring about actual insects, they’re suffering from delusional parasitosis, and they’re desperate and even suicidal.
When you can’t wait for the world’s longest meeting to end, the mindless leg bouncing makes your boredom obvious and just annoys everybody else. Everyone knows the TPS reports need the damn cover sheet, but some sadistic colleague keeps forgetting, probably on purpose just to eat into your lunch hour. Enough is enough!While serving a […]
What could be more fun than a slingshot that shoots tiny airplanes? A slingshot that shoots tiny glowing airplanes of course! These toy planes are outfitted with ultra-bright LEDs, so you can fly all night without losing them in the trees.Whether you are a regular-sized child, or an overgrown adult one, these light-up flyers offer […]
You know the drill. You go to the dentist and they ask you how often you floss. You lie through your teeth and say, “every day!” (Bonus points if you have some cilantro or chives stuck in your gums from lunch). You don’t want to keep up the charade any longer, but rubbing that tiny strand […]