A word of caution to people who consume illegal stimulants and those who regularly take legal ones to treat the symptoms mental health issues, like ADHD or depression. Research is showing that, during heat waves, there is an increased risk of death among stimulant users. It's a small increase—Time magazine reported that "for every week that the temperature exceeds 75 degrees Fahrenheit, New York City will experience two extra cocaine-related deaths." And it seems to affect people taking particularly high doses. But, depending on the dosages you normally take, it could be a risk worth taking into account.
Heat and high doses combine in dangerous ways for a couple of reasons:
First, stimulants themselves raise body temperature, which is not what you want during a heat wave. They also interfere with the body's ability to regulate temperature to cool itself down. The high body temperatures that result are one way that stimulant overdose kills—so extra heat makes matters worse.
Secondly, chemical reactions that injure or kill brain cells can occur when high doses of these drugs are taken. These may be more toxic when the temperature is higher. High doses of stimulants cause excess release of dopamine and glutamate— if these levels get high enough, the resulting chemical reactions can be deadly to cells. That process may increase overdose risk as well as contributing to long-term harm in those who survive.
Via All Things Human
