A plant known as "birthwort," popular in Asian and European herbal medicine for hundreds of years, causes kidney failure and cancer. Dan Vergano at USA Today digs into the fascinating medical detective work that solved this mystery: scientists compared genetic mutations in the tissue of humans and lab mice who'd been poisoned by the plant's toxic component:
"The big clue was the plant itself," says pharmacologist Arthur Grollman of Stony Brook (N.Y.) University. "Once it was appreciated that it contained a potent kidney toxin and human carcinogen, we could get to the bottom of things."
Grollman and colleagues have unraveled a genetic signature left behind by birthwort in cases of cancers and kidney failure, as reported in the March journal of Kidney International. And in upcoming work, they report signs that use of the drug in Chinese medicines may be responsible for Taiwan's sky-high rate of kidney disease.
Read more: Herbal 'remedy' may trigger widespread kidney failure – USATODAY.com.
Artists Jeff Louviere and Vanessa Brown explore cymatics, the study of wave phenomena and how they are represented visually. Using black-colored water, a laptop computer, and a modified guitar amp, they captured “portraits” of the 12 notes in the chromatic scale. From my sister-in-law Heather Sparks’s profile of their project in Nautilus: In each (“portrait”), […]
Yesterday’s science-by-press-release announcement that a research team had made a “breakthrough” in treating ALS thanks to funds raised in last year’s viral ice-bucket challenge turns out to be vaporware: the gene identified was already known to be implicated in ALS, but only affects 3% of cases, and the new refinement in the research suggests some […]
New research on trends in adult human height over the last century confirm that, no surprise, humans are getting taller overall due to better nutrition and disease control. However according to the health science group Non-Communicable Diseases Risk Factor Collaboration (NCD-RisC), the gain in adult height varies dramatically by country. From their paper, published in […]
Those of us who love music wish we could listen to it 24/7. But it’s impossible when we’re trying to converse with our friends, or when are swimming in the local pool.That is, until now. The KOAR Bone Conduction Bluetooth Headset, now 48% off, has changed the audio game.Made with lightweight titanium memory metal, this headset boasts patented bone conduction technology to transport sound […]
It’s one thing to enjoy dinner at home and a nice glass of Cabernet Sauvignon with your best friend, Netflix, but it’s another thing entirely to make that meal from scratch and get that wine delivered right to your doorstep.But what if we told you there’s a way to make this possible? To keep your social life, […]
Having to pack and drag your stuff through security can put quite the damper on your vacation plans. Thankfully, we’ve got your back with one way to make traveling more painless: the Jumper Overnighter Travel Bag.This compact bag is so lightweight that you can effortlessly carry it, and fit it into any overhead compartment. But just […]