A plant known as "birthwort," popular in Asian and European herbal medicine for hundreds of years, causes kidney failure and cancer. Dan Vergano at USA Today digs into the fascinating medical detective work that solved this mystery: scientists compared genetic mutations in the tissue of humans and lab mice who'd been poisoned by the plant's toxic component:
"The big clue was the plant itself," says pharmacologist Arthur Grollman of Stony Brook (N.Y.) University. "Once it was appreciated that it contained a potent kidney toxin and human carcinogen, we could get to the bottom of things."
Grollman and colleagues have unraveled a genetic signature left behind by birthwort in cases of cancers and kidney failure, as reported in the March journal of Kidney International. And in upcoming work, they report signs that use of the drug in Chinese medicines may be responsible for Taiwan's sky-high rate of kidney disease.
Read more: Herbal 'remedy' may trigger widespread kidney failure – USATODAY.com.
More than 800 American energy and Earth science researchers have signed a letter to Donald Trump outlining six steps they’re urging him to take to address human-caused climate change to protect “America’s economy, national security, and public health and safety.” The letter is accompanied by a public change.org petition to “Tell Trump To #ActOnClimate.” Here […]
James Delingpole is an invective-hurling anti-climate science columnist who has candidly admitted that he doesn’t bother to read scientific papers, calling himself a “an interpreter of interpretations.”
Kratom (previously) is a widely used herb that has been very effective in treating opioid withdrawal and other chronic, hard-to-treat conditions — it also became very controversial this year because the DEA decided, without evidence, to class it as a dangerous drug, and then changed its mind (unprecedented!) after a mass-scale petition that included interventions […]
The Boing Boing Store’s Gift Guide is full of ideas for pretty much anyone in your life like hipster ice cub trays, Xbox controllers, Halo Boards, and even diamond necklaces. As always, all products in the Boing Boing Store come at great discounts, too. Shop by price bucket starting at under $20. Under $20:Bloxx Jumbo Ice Trays […]
Unlike traditional lighters, the SaberLight features an electronic plasma beam that’s both rechargeable and butane-free. This sleek lighter is even approved by TSA, so you’ll never be stuck buying lighters you’ll just have to throw away partially used. For some people, like me, this is a pretty big game-changer. The SaberLight’s beam is actually both hotter and cleaner […]
Holiday shopping is in full swing, and the Striiv Touch is one of the best gift ideas I’ve landed on. Its simple design works for females and males, and its wide range of features makes it suitable for even the non-fitness enthusiasts in your life.Unlike traditional fitness trackers, the Striiv Touch also acts as a smartwatch. It […]