A plant known as "birthwort," popular in Asian and European herbal medicine for hundreds of years, causes kidney failure and cancer. Dan Vergano at USA Today digs into the fascinating medical detective work that solved this mystery: scientists compared genetic mutations in the tissue of humans and lab mice who'd been poisoned by the plant's toxic component:
"The big clue was the plant itself," says pharmacologist Arthur Grollman of Stony Brook (N.Y.) University. "Once it was appreciated that it contained a potent kidney toxin and human carcinogen, we could get to the bottom of things."
Grollman and colleagues have unraveled a genetic signature left behind by birthwort in cases of cancers and kidney failure, as reported in the March journal of Kidney International. And in upcoming work, they report signs that use of the drug in Chinese medicines may be responsible for Taiwan's sky-high rate of kidney disease.
Read more: Herbal 'remedy' may trigger widespread kidney failure – USATODAY.com.
Beatboxer Tom Thum had ENT doctor and laryngeal surgeon Dr Matthew Broadhurst shine an endoscopic camera down his throat while beatboxing: “I wanted to find out how my larynx functioned when beatboxing compared to how it functions normally with speech, and whether or not there were any abnormalities in my laryngeal anatomy. I also had […]
Gastric bypass surgery is remarkably effective at promoting weight-loss (it cuts the long-term risk of early death from morbid obesity by 40%), and it’s long been presumed that the major action by which it worked was that, by bypassing the parts of the gut where most food absorbtion takes place, it limited the calories that […]
Timothy writes, “Diego Gómez is a Colombian conservation biologist. When he was a college student, he shared a single research paper online so that others could read and learn from it, just as he did. Diego was criminally prosecuted for copyright infringement, and faced up to 8 years in prison.”
If you don’t want to get stuck footing the bill for a hit and run, this dashboard-mounted camera offers up to 2K resolution to make sure you always have a reliable witness, and it’s available in the Boing Boing Store for 30% off it’s usual price.The PapaGo mounts unobtrusively to your windshield to see everything […]
While some people still maintain that everything in Apple’s walled garden “just works” and is immune to the rampant malware of the Windows world, the reality is different. The Mac’s growing market share has made it a much more viable target for malicious actors, and its built-in tools aren’t always enough to fix things. Drive […]
Boasting an IPX6 waterproof rating, the Trakk Bullet Ultra Compact Waterproof Bluetooth Speaker resists dust and heavy rainfall. It’s currently available in the Boing Boing Store.The Trakk Bullet offers the same wireless convenience as other portable speakers, but few are built as tough as this one. Its utilitarian construction is designed to be a totally low-maintenance […]