In the journal Nature, interesting stem cell news that could lead to more effectively-targeted chemotherapy for cancer patients. Part of why chemo is so brutal is that it targets all fast-growing cells within the body—the ones that want to kill you, and ones that keep you alive, all are attacked. I've been through it, and it's pretty awful. Snip:
Cancer researchers can sequence tumour cells’ genomes, scan them for strange gene activity, profile their contents for telltale proteins and study their growth in laboratory dishes. What they have not been able to do is track errant cells doing what is more relevant to patients: forming tumours. Now three groups studying tumours in mice have done exactly that. Their results support the ideas that a small subset of cells drives tumour growth and that curing cancer may require those cells to be eliminated.
It is too soon to know whether these results — obtained for tumours of the brain, the gut and the skin — will apply to other cancers, says Luis Parada at the University of Texas Southwestern Medical Center in Dallas, who led the brain study. But if they do, he says, “there is going to be a paradigm shift in the way that chemotherapy efficacy is evaluated and how therapeutics are developed”. Instead of testing whether a therapy shrinks a tumour, for instance, researchers would assess whether it kills the right sorts of cell.
More: Cancer stem cells tracked : Nature News & Comment.
Photo: (Nature.com/G. DRIESSENS). Researchers can now trace the cell lineage within a growing tumor. In this skin tumor, the red cells all originated from one stem cell.
Artists Jeff Louviere and Vanessa Brown explore cymatics, the study of wave phenomena and how they are represented visually. Using black-colored water, a laptop computer, and a modified guitar amp, they captured “portraits” of the 12 notes in the chromatic scale. From my sister-in-law Heather Sparks’s profile of their project in Nautilus: In each (“portrait”), […]
Yesterday’s science-by-press-release announcement that a research team had made a “breakthrough” in treating ALS thanks to funds raised in last year’s viral ice-bucket challenge turns out to be vaporware: the gene identified was already known to be implicated in ALS, but only affects 3% of cases, and the new refinement in the research suggests some […]
New research on trends in adult human height over the last century confirm that, no surprise, humans are getting taller overall due to better nutrition and disease control. However according to the health science group Non-Communicable Diseases Risk Factor Collaboration (NCD-RisC), the gain in adult height varies dramatically by country. From their paper, published in […]
Those of us who love music wish we could listen to it 24/7. But it’s impossible when we’re trying to converse with our friends, or when are swimming in the local pool.That is, until now. The KOAR Bone Conduction Bluetooth Headset, now 48% off, has changed the audio game.Made with lightweight titanium memory metal, this headset boasts patented bone conduction technology to transport sound […]
It’s one thing to enjoy dinner at home and a nice glass of Cabernet Sauvignon with your best friend, Netflix, but it’s another thing entirely to make that meal from scratch and get that wine delivered right to your doorstep.But what if we told you there’s a way to make this possible? To keep your social life, […]
Having to pack and drag your stuff through security can put quite the damper on your vacation plans. Thankfully, we’ve got your back with one way to make traveling more painless: the Jumper Overnighter Travel Bag.This compact bag is so lightweight that you can effortlessly carry it, and fit it into any overhead compartment. But just […]