In the journal Nature, interesting stem cell news that could lead to more effectively-targeted chemotherapy for cancer patients. Part of why chemo is so brutal is that it targets all fast-growing cells within the body—the ones that want to kill you, and ones that keep you alive, all are attacked. I've been through it, and it's pretty awful. Snip:
Cancer researchers can sequence tumour cells’ genomes, scan them for strange gene activity, profile their contents for telltale proteins and study their growth in laboratory dishes. What they have not been able to do is track errant cells doing what is more relevant to patients: forming tumours. Now three groups studying tumours in mice have done exactly that. Their results support the ideas that a small subset of cells drives tumour growth and that curing cancer may require those cells to be eliminated.
It is too soon to know whether these results — obtained for tumours of the brain, the gut and the skin — will apply to other cancers, says Luis Parada at the University of Texas Southwestern Medical Center in Dallas, who led the brain study. But if they do, he says, “there is going to be a paradigm shift in the way that chemotherapy efficacy is evaluated and how therapeutics are developed”. Instead of testing whether a therapy shrinks a tumour, for instance, researchers would assess whether it kills the right sorts of cell.
More: Cancer stem cells tracked : Nature News & Comment.
Photo: (Nature.com/G. DRIESSENS). Researchers can now trace the cell lineage within a growing tumor. In this skin tumor, the red cells all originated from one stem cell.
After years of speculation and wrangling over his remains, Kennewick Man turns out to be closely related to contemporary, local Native Americans after all. Discovered near Kennewick, Wash., in 1996, the skeleton ended up in a tug of war between tribes in the pacific northwest who wanted to bury the remains, and scientists who wanted […]
Our solar system is awesome.
The European Organization for Nuclear Research, or CERN, has been releasing portions of its research to the public for years. This week’s massive 300 terabyte dump of Large Hadron Collider (LHC) data is the biggest yet by a long shot — and it’s all out there, open source, free for the exploration.
You may not love Microsoft Word, but you’ve definitely used it. Other than being one of the most ubiquitous programs on the planet, it’s been the go-to word processing system for more than a quarter-century because it’s as basic as it gets. But occasionally, you’ve got assignments that beg for a lot more options than simple […]
Almost everyone has their smartphone in a case of one kind or another. Beyond simple protection, finding a case that can charge your phone on its own, but doesn’t feel like it’s also adding a couple pounds to the phone’s weight is the tricky part. Billed as the world’s thinnest battery case, the ThinCharge iPhone […]
You never know when new projects, ideas or opportunities can drop into your lap at a moment’s notice. That may require you to learn a new programming language like Python. Or maybe you need a primer on 3D game development. Or you might realize you could use a serious brush-up on iOS mobile creation.Point is, […]