In the journal Nature, interesting stem cell news that could lead to more effectively-targeted chemotherapy for cancer patients. Part of why chemo is so brutal is that it targets all fast-growing cells within the body—the ones that want to kill you, and ones that keep you alive, all are attacked. I've been through it, and it's pretty awful. Snip:
Cancer researchers can sequence tumour cells’ genomes, scan them for strange gene activity, profile their contents for telltale proteins and study their growth in laboratory dishes. What they have not been able to do is track errant cells doing what is more relevant to patients: forming tumours. Now three groups studying tumours in mice have done exactly that. Their results support the ideas that a small subset of cells drives tumour growth and that curing cancer may require those cells to be eliminated.
It is too soon to know whether these results — obtained for tumours of the brain, the gut and the skin — will apply to other cancers, says Luis Parada at the University of Texas Southwestern Medical Center in Dallas, who led the brain study. But if they do, he says, “there is going to be a paradigm shift in the way that chemotherapy efficacy is evaluated and how therapeutics are developed”. Instead of testing whether a therapy shrinks a tumour, for instance, researchers would assess whether it kills the right sorts of cell.
More: Cancer stem cells tracked : Nature News & Comment.
Photo: (Nature.com/G. DRIESSENS). Researchers can now trace the cell lineage within a growing tumor. In this skin tumor, the red cells all originated from one stem cell.
A trio of scholars who study the psychology and philosophy of science have written a fantastic paper for Springer’s Sythese looking at the way that climate change conspiracy theorists construct their view of the world, and how these conspiracy theories contain self-contradictory theses (like the idea that climate change can’t be predicted and the idea […]
Princeton University psych prof Susan Fiske published an open letter denouncing the practice of using social media to call out statistical errors in psychology research, describing the people who do this as “terrorists” and arguing that this was toxic because of the structure of social science scholarship, having an outsized effect on careers.
Blue writes, “Peter Watts has be stricken with debilitating pain, loss of range of motion and motor control. Watts’ doctors remain baffled despite a battery of tests, and Watts has reached out to his fans to ask for their theories and ideas as to what might be causing his illness.”
CloudPress is a responsive WordPress theme builder that allows you to create a whole site in less than 30 minutes. CloudPress comes with tools like pre-built headers, content blocks, and footers—all you have to do is pick what you like, and drag and drop. With your subscription, you get access to 13 professionally designed WordPress themes, over 80 […]
If you own a dog, you’ve most likely heard of BarkBox – the monthly subscription box for dogs. What started as a simple idea to try out the subscription model on pet owners has since developed a cult following of dog lovers. If you haven’t given it a try yet, this one month free deal is the […]
With the iPhone headphone jack having gone by the wayside, we’re excited about the addition of the FRANKLIN Bluetooth Headphones in our store. These headphones are foldable so they’re easy to carry around, but most importantly, they pack impressive sound. Our biggest struggle with Bluetooth headphones is the worry of them dying at the worst moment. This pair lasts an impressive 8-10 […]