In the journal Nature, interesting stem cell news that could lead to more effectively-targeted chemotherapy for cancer patients. Part of why chemo is so brutal is that it targets all fast-growing cells within the body—the ones that want to kill you, and ones that keep you alive, all are attacked. I've been through it, and it's pretty awful. Snip:
Cancer researchers can sequence tumour cells’ genomes, scan them for strange gene activity, profile their contents for telltale proteins and study their growth in laboratory dishes. What they have not been able to do is track errant cells doing what is more relevant to patients: forming tumours. Now three groups studying tumours in mice have done exactly that. Their results support the ideas that a small subset of cells drives tumour growth and that curing cancer may require those cells to be eliminated.
It is too soon to know whether these results — obtained for tumours of the brain, the gut and the skin — will apply to other cancers, says Luis Parada at the University of Texas Southwestern Medical Center in Dallas, who led the brain study. But if they do, he says, “there is going to be a paradigm shift in the way that chemotherapy efficacy is evaluated and how therapeutics are developed”. Instead of testing whether a therapy shrinks a tumour, for instance, researchers would assess whether it kills the right sorts of cell.
More: Cancer stem cells tracked : Nature News & Comment.
Photo: (Nature.com/G. DRIESSENS). Researchers can now trace the cell lineage within a growing tumor. In this skin tumor, the red cells all originated from one stem cell.
SmarterEveryDay’s Destin Sandlin captured this astonishing video of the International Space Station transiting Monday’s solar eclipse. Fast forward to 3:50 for the magical moment. And in case you missed it, below is NASA’s still photo of the ISS transiting the sun at five miles per second.
The psilocybin in magic mushrooms is a potent psychedelic for animals. But what good is the psilocybin for the shrooms? New genetic research from Ohio State University suggests that the psilocybin might act as an insect repellant, protecting the mushrooms. From New Scientist: The gene cluster (linked to psilocybin production) is found in several distantly […]
In elementary school, I knew a boy who would impress us by pulling the legs off a daddy longlegs and popping the body in his mouth. I think he would appreciate this Deep Look video about how daddy longlegs can drop up to three of its limbs when threatened by a predator and still survive.
Top-performing content doesn’t come from pure inspiration. So how do you get the maximum number of eyeballs to see your marketing copy? By analyzing the impact of the keywords within. Serpstat does this all for you. It can monitor up to 200 keywords in your projects, across 10 total domains. They keep track of the […]
Toaster ovens are the perfect appliance for small things like toasted sandwiches and roasted garlic (try it!), but anything more involved usually requires a full-sized conventional oven.However, despite its small size, the Wolfgang Puck Pressure Oven can handle anything from baked pastries to broiled meats. This kitchen appliance has a minimal countertop footprint, and cooks […]