In the journal Nature, interesting stem cell news that could lead to more effectively-targeted chemotherapy for cancer patients. Part of why chemo is so brutal is that it targets all fast-growing cells within the body—the ones that want to kill you, and ones that keep you alive, all are attacked. I've been through it, and it's pretty awful. Snip:
Cancer researchers can sequence tumour cells’ genomes, scan them for strange gene activity, profile their contents for telltale proteins and study their growth in laboratory dishes. What they have not been able to do is track errant cells doing what is more relevant to patients: forming tumours. Now three groups studying tumours in mice have done exactly that. Their results support the ideas that a small subset of cells drives tumour growth and that curing cancer may require those cells to be eliminated.
It is too soon to know whether these results — obtained for tumours of the brain, the gut and the skin — will apply to other cancers, says Luis Parada at the University of Texas Southwestern Medical Center in Dallas, who led the brain study. But if they do, he says, “there is going to be a paradigm shift in the way that chemotherapy efficacy is evaluated and how therapeutics are developed”. Instead of testing whether a therapy shrinks a tumour, for instance, researchers would assess whether it kills the right sorts of cell.
More: Cancer stem cells tracked : Nature News & Comment.
Photo: (Nature.com/G. DRIESSENS). Researchers can now trace the cell lineage within a growing tumor. In this skin tumor, the red cells all originated from one stem cell.
Apple released this lovely new commercial featuring Carl Sagan reading from his magnificent 1994 book Pale Blue Dot: A Vision of the Human Future in Space, now available as an audiobook. This surprising partnership spurred Adweek to interview my friend Ann Druyan, Sagan’s wife, collaborator, and creative director of the Voyager Golden Record, about being […]
The Action Lab took a maglev gyroscope and placed it inside a sealed chamber to see what happens to a levitating gyroscope in a vacuum. A lot of people took issue with the experiment’s setup and explanation, but it’s interesting nonetheless. He responded to those concerns: Hi everyone! I see a lot of comments that […]
Shocking footage, taken from a nearby aircraft, shows a jetliner spraying its appalling chemical payload into our skies. Traffic 12 o'clock pic.twitter.com/g5QjlQ5v8z— Airplane Pictures ✈ (@iLove_Aviation) June 19, 2017
Even though credit cards now feature an EMV chip for securing transactions, they still have to include the magnetic strip for compatibility with older point of sale systems. Because of this, there’s no way for the chip’s new security capabilities to protect against card skimmers in the wild.How do you protect yourself from legacy-technology-induced fraud? […]
As the old saying goes, “You should sit in meditation for 30 minutes every day. Unless you are too busy, in which case you should meditate for an hour.” Since most of us have an endless list of things to do and people to see, carving out quiet time can feel impossible, especially when most […]
The Bragi Dash Truly Wireless Smart Earphones are far more than your run of the mill Bluetooth earbuds. While the earpiece design makes these earbuds ideal for exercise and activity, and passive noise cancelling is conducive to a more serene listening experience, these buds go well beyond just playing music.First of all, they can actually […]