The tl;dr: If a medical study seems too good to be true, it probably is. Eryn Brown in the Los Angeles Times writes about
a statistical analysis of nearly 230,000 trials compiled from a variety of disciplines, published today in the Journal of the American Medical Association. The analysis by Stanford's Dr. John Ioannidis and a team of fellow researchers looked at study results claiming a "very large effect," and found that those claims seldom ended up being true when other research teams tried to repeat the same results.
One such example: the cancer drug Avastin. Clinical trials suggested the drug might double the time breast cancer patients could live with their disease without getting worse. But follow-up studies found no improvements in progression-free survival, overall survival or patients' quality of life. As a result, the U.S. Food and Drug Administration in 2011 withdrew its approval to use the drug to treat breast cancer, though it is still approved to treat several other types of cancer.
With early glowing reports, Ioannidis said, "one should be cautious and wait for a better trial."
Read the full LAT article. Here's the JAMA paper, but you have to be a paid subscriber to read it.
Writing in Slate, Cathy “Weapons of Math Destruction” O’Neill, a skeptical data-scientist, describes the ways that Big Data intersects with ethical considerations.
Our pals at surreal clothiers Imaginary Foundation bring us this fine enamel pin emblazoned with an essential insight of the ages, captured by a simple Venn diagram. Just $10!
In his weekly address, President Barack Obama this week pledged $4 billion in federal funding for computer science education in schools throughout the nation.
You travel around a lot. It might be that jet set life from New York to LA to London to Tokyo, or it might be back and forth from the coffee shop to the office, or from the kitchen to the couch. Any which way, you’re mobile and that’s the way to live. When you […]
It’s 2016 and we like our technology really small. Our phones fit in our pockets, our remotes are lighter than ever, and even our cars seem to be shrinking. So your new drone shouldn’t be an exception. This Axis VIDIUS Drone is 21% off right now and it’s so little, your biggest problem won’t be […]
You’ve heard the news: cyber security is the new and very scary frontier. Hackers are out there just waiting for you to relax for a second and let them in. But that’s not going to happen to you. With a lifetime premium subscription to ZenMate VPN, you’re completely protected from anyone out there who wants […]