How much caffeine is too much caffeine?

Discuss

16 Responses to “How much caffeine is too much caffeine?”

  1. Promethean Sky says:

    3 cups? In my family that will barely get you alert enough to make another pot.

  2. s2redux says:

    Futurama did this research in 2003 (or maybe it was 3003). One not-unexpected finding: 100 cups puts you into bullet-time.

  3. nmcvaugh says:

    But if you can push through that 75 cup barrier:

    http://www.youtube.com/watch?v=gILlaMTuOt4

    You will be able to transcend time itself:

    http://www.youtube.com/watch?v=C9Ef0ErCU1c

    Or so I’ve seen on TV.

  4. Rich Keller says:

    I’m trying to cut down on my jitter candy intake.

  5. Wreckrob8 says:

    8oz cups? How unamerican!

  6. theophrastvs says:

    chocolatecoveredespressobeans!!! [zig-zat...]

  7. yeah but it takes at least 6 cups a day to counter-balance my heroin habit.

  8. Neowolf says:

    Probably depends on whether you have the fast metabolizer version of CYP1A2.

  9. Thomas Schmidt says:

    Coffee must be like Iocane… I have developed an immunity to large doses :-)

  10. dioptase says:

    I did these calculations about 9 years ago. Forgive the cut and paste.

    Caffeine LD50 (50/50 chance of killing you) is 150 mg/kg.
    Half life of 5-7 hours with extremes of 3 to 20 hours common.

    Coffee has 93 to 164 mg/5oz serving.

    I’m a big guy, 100kg, so could stand 15g before having a better than even chance of dying. Drinking 100 cups of the hard stuff at once would be a bad idea (16.4 g).

    But drink a cup of the hard stuff every 14.4 minutes and it never goes over 6.4 g (assuming a 7 hour half life).

    Now try some small woman, say 45 kg. Her limit is 6.75 gm. Might be ok or a risk, less than 50%, of dying. But if she’s on the pill, her metabolism half life is 13 hours. She hits exceed 9.3 g. Well above LD50 so probably a goner.

    Your mileage may vary.

    References:

    http://codeine.50g.com/other/caffeine.html
    http://www.chinamist.com/knowledge/health/caffeine /content.htm
    http://www.erowid.org/chemicals/caffeine/caffeine_ effects.shtm

  11. adonai says:

    75 cups?

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