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	<title>Comments on: How much caffeine is too much&#160;caffeine?</title>
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	<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html</link>
	<description>Brain candy for Happy Mutants</description>
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	<item>
		<title>By: Gyrofrog</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1648147</link>
		<dc:creator>Gyrofrog</dc:creator>
		<pubDate>Wed, 06 Feb 2013 19:59:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1648147</guid>
		<description> aka Buzzballs</description>
		<content:encoded><![CDATA[<p> aka Buzzballs</p>
]]></content:encoded>
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		<title>By: adonai</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1647053</link>
		<dc:creator>adonai</dc:creator>
		<pubDate>Tue, 05 Feb 2013 22:50:00 +0000</pubDate>
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		<description>75 cups?</description>
		<content:encoded><![CDATA[<p>75 cups?</p>
]]></content:encoded>
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	<item>
		<title>By: Antinous / Moderator</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646862</link>
		<dc:creator>Antinous / Moderator</dc:creator>
		<pubDate>Tue, 05 Feb 2013 20:58:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646862</guid>
		<description>A cup of tea is enough to kick me into SVT.</description>
		<content:encoded><![CDATA[<p>A cup of tea is enough to kick me into SVT.</p>
]]></content:encoded>
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		<title>By: dioptase</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646778</link>
		<dc:creator>dioptase</dc:creator>
		<pubDate>Tue, 05 Feb 2013 20:02:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646778</guid>
		<description>I did these calculations about 9 years ago.  Forgive the cut and paste.

Caffeine LD50 (50/50 chance of killing you) is 150 mg/kg.  
Half life of 5-7 hours with extremes of 3 to 20 hours common. 

Coffee has 93 to 164 mg/5oz serving.

I&#039;m a big guy, 100kg, so could stand 15g before having a better than even chance of dying.  Drinking 100 cups of the hard stuff at once would be a bad idea (16.4 g). 

But drink a cup of the hard stuff every 14.4 minutes and it never goes over 6.4 g (assuming a 7 hour half life).

Now try some small woman, say 45 kg.  Her limit is 6.75 gm.  Might be ok or a risk, less than 50%, of dying.  But if she&#039;s on the pill, her metabolism half life is 13 hours.  She hits exceed 9.3 g.  Well above LD50 so probably a goner.

Your mileage may vary.

References:

http://codeine.50g.com/other/caffeine.html
http://www.chinamist.com/knowledge/health/caffeine  /content.htm
http://www.erowid.org/chemicals/caffeine/caffeine_  effects.shtm</description>
		<content:encoded><![CDATA[<p>I did these calculations about 9 years ago.  Forgive the cut and paste.</p>
<p>Caffeine LD50 (50/50 chance of killing you) is 150 mg/kg.<br />
Half life of 5-7 hours with extremes of 3 to 20 hours common. </p>
<p>Coffee has 93 to 164 mg/5oz serving.</p>
<p>I&#8217;m a big guy, 100kg, so could stand 15g before having a better than even chance of dying.  Drinking 100 cups of the hard stuff at once would be a bad idea (16.4 g). </p>
<p>But drink a cup of the hard stuff every 14.4 minutes and it never goes over 6.4 g (assuming a 7 hour half life).</p>
<p>Now try some small woman, say 45 kg.  Her limit is 6.75 gm.  Might be ok or a risk, less than 50%, of dying.  But if she&#8217;s on the pill, her metabolism half life is 13 hours.  She hits exceed 9.3 g.  Well above LD50 so probably a goner.</p>
<p>Your mileage may vary.</p>
<p>References:</p>
<p><a href="http://codeine.50g.com/other/caffeine.html" rel="nofollow">http://codeine.50g.com/other/caffeine.html</a><br />
<a href="http://www.chinamist.com/knowledge/health/caffeine" rel="nofollow">http://www.chinamist.com/knowledge/health/caffeine</a>  /content.htm<br />
<a href="http://www.erowid.org/chemicals/caffeine/caffeine_" rel="nofollow">http://www.erowid.org/chemicals/caffeine/caffeine_</a>  effects.shtm</p>
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		<title>By: Thomas Schmidt</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646753</link>
		<dc:creator>Thomas Schmidt</dc:creator>
		<pubDate>Tue, 05 Feb 2013 19:47:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646753</guid>
		<description>Coffee must be like Iocane... I have developed an immunity to large doses :-)</description>
		<content:encoded><![CDATA[<p>Coffee must be like Iocane&#8230; I have developed an immunity to large doses :-)</p>
]]></content:encoded>
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	<item>
		<title>By: Neowolf</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646737</link>
		<dc:creator>Neowolf</dc:creator>
		<pubDate>Tue, 05 Feb 2013 19:32:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646737</guid>
		<description>Probably depends on whether you have the fast metabolizer version of CYP1A2. </description>
		<content:encoded><![CDATA[<p>Probably depends on whether you have the fast metabolizer version of CYP1A2. </p>
]]></content:encoded>
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		<title>By: Cameron Postelwait</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646643</link>
		<dc:creator>Cameron Postelwait</dc:creator>
		<pubDate>Tue, 05 Feb 2013 18:32:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646643</guid>
		<description>yeah but it takes at least 6 cups a day to counter-balance my heroin habit.</description>
		<content:encoded><![CDATA[<p>yeah but it takes at least 6 cups a day to counter-balance my heroin habit.</p>
]]></content:encoded>
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		<title>By: GawainLavers</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646625</link>
		<dc:creator>GawainLavers</dc:creator>
		<pubDate>Tue, 05 Feb 2013 18:25:00 +0000</pubDate>
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		<description>Huh...I consider myself a lightweight because after 1 mug I&#039;m good, but two mugs and I&#039;m too hyper to focus.  But those are 24oz mugs.</description>
		<content:encoded><![CDATA[<p>Huh&#8230;I consider myself a lightweight because after 1 mug I&#8217;m good, but two mugs and I&#8217;m too hyper to focus.  But those are 24oz mugs.</p>
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	<item>
		<title>By: s2redux</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646621</link>
		<dc:creator>s2redux</dc:creator>
		<pubDate>Tue, 05 Feb 2013 18:23:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646621</guid>
		<description>You owe me a Coke! &lt;g&gt;</description>
		<content:encoded><![CDATA[<p>You owe me a Coke! &lt;g&gt;</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Wreckrob8</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646603</link>
		<dc:creator>Wreckrob8</dc:creator>
		<pubDate>Tue, 05 Feb 2013 18:11:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646603</guid>
		<description>8oz cups? How unamerican!</description>
		<content:encoded><![CDATA[<p>8oz cups? How unamerican!</p>
]]></content:encoded>
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	<item>
		<title>By: theophrastvs</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646606</link>
		<dc:creator>theophrastvs</dc:creator>
		<pubDate>Tue, 05 Feb 2013 18:11:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646606</guid>
		<description>chocolatecoveredespressobeans!!! [zig-zat...]</description>
		<content:encoded><![CDATA[<p>chocolatecoveredespressobeans!!! [zig-zat...]</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: Wreckrob8</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646596</link>
		<dc:creator>Wreckrob8</dc:creator>
		<pubDate>Tue, 05 Feb 2013 18:05:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646596</guid>
		<description>I just treat myself to a couple of quadruple espressos on a Sunday now. I don&#039;t miss my daily dose at all.</description>
		<content:encoded><![CDATA[<p>I just treat myself to a couple of quadruple espressos on a Sunday now. I don&#8217;t miss my daily dose at all.</p>
]]></content:encoded>
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		<title>By: Rich Keller</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646563</link>
		<dc:creator>Rich Keller</dc:creator>
		<pubDate>Tue, 05 Feb 2013 17:49:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646563</guid>
		<description>I&#039;m trying to cut down on my jitter candy intake.</description>
		<content:encoded><![CDATA[<p>I&#8217;m trying to cut down on my jitter candy intake.</p>
]]></content:encoded>
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	<item>
		<title>By: s2redux</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646536</link>
		<dc:creator>s2redux</dc:creator>
		<pubDate>Tue, 05 Feb 2013 17:32:00 +0000</pubDate>
		<guid isPermaLink="false">http://boingboing.net/?p=210953#comment-1646536</guid>
		<description>&lt;i&gt;Futurama&lt;/i&gt; &lt;a href=&quot;http://www.youtube.com/watch?v=gILlaMTuOt4&quot; rel=&quot;nofollow&quot;&gt;did this research&lt;/a&gt; in 2003 (or maybe it was 3003). One not-unexpected finding: &lt;a href=&quot;http://www.youtube.com/watch?v=C9Ef0ErCU1c&quot; rel=&quot;nofollow&quot;&gt;100 cups&lt;/a&gt; puts you into bullet-time.</description>
		<content:encoded><![CDATA[<p><i>Futurama</i> <a href="http://www.youtube.com/watch?v=gILlaMTuOt4" rel="nofollow">did this research</a> in 2003 (or maybe it was 3003). One not-unexpected finding: <a href="http://www.youtube.com/watch?v=C9Ef0ErCU1c" rel="nofollow">100 cups</a> puts you into bullet-time.</p>
]]></content:encoded>
	</item>
	<item>
		<title>By: nmcvaugh</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646537</link>
		<dc:creator>nmcvaugh</dc:creator>
		<pubDate>Tue, 05 Feb 2013 17:32:00 +0000</pubDate>
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		<description>But if you can push through that 75 cup barrier:

http://www.youtube.com/watch?v=gILlaMTuOt4

You will be able to transcend time itself:

http://www.youtube.com/watch?v=C9Ef0ErCU1c

Or so I&#039;ve seen on TV.</description>
		<content:encoded><![CDATA[<p>But if you can push through that 75 cup barrier:</p>
<p><a href="http://www.youtube.com/watch?v=gILlaMTuOt4" rel="nofollow">http://www.youtube.com/watch?v=gILlaMTuOt4</a></p>
<p>You will be able to transcend time itself:</p>
<p><a href="http://www.youtube.com/watch?v=C9Ef0ErCU1c" rel="nofollow">http://www.youtube.com/watch?v=C9Ef0ErCU1c</a></p>
<p>Or so I&#8217;ve seen on TV.</p>
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		<title>By: Promethean Sky</title>
		<link>http://boingboing.net/2013/02/05/how-much-caffeine-is-too-much.html#comment-1646522</link>
		<dc:creator>Promethean Sky</dc:creator>
		<pubDate>Tue, 05 Feb 2013 17:20:00 +0000</pubDate>
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		<description>3 cups? In my family that will barely get you alert enough to make another pot. </description>
		<content:encoded><![CDATA[<p>3 cups? In my family that will barely get you alert enough to make another pot. </p>
]]></content:encoded>
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