Original art for 1973 Spider-Man cover has current high bid of $268, 875

Live bidding on the Johnny Romita's cover art for Amazing Spider-Man #121 has commenced at Heritage Auctions.
The loss of Gwen marked nothing less than an end to the carefree fun and offbeat innocence of the Silver Age era. Spider-Man and the Marvel Age of Heroes were never quite so merry after this story.

John Romita Sr. Amazing Spider-Man #121 "The Night Gwen Stacy Died"

(Via CBR)

Previously:
Batman drawing sells for $448,125