I finally got around to reading Carl Zimmer's highly-recommended National Geographic
article about antibiotics and their effect on our microbiome, the "100 trillion microbes that live in our healthy bodies."
Scientists are only now beginning to get answers to those questions. In a paper just published online in the journal Gut, Andres Moya of the University of Valencia and his colleagues took an unprecedented look at a microbiome weathering a storm of antibiotics. The microbiome belonged to a 68-year-old man who had developed an infection in his pacemaker. A two-week course of antbiotics cleared it up nicely. Over the course of his treatment, Moya and his colleagues collected stool samples from the man every few days, and then six weeks afterwards. They identified the species in the stool, as well as the genes that the bacteria switched on and off.
What’s most striking about Moya’s study is how the entire microbiome responded to the antibiotics as if it was under a biochemical mortar attack. The bacteria started producing defenses to keep the deadly molecules from getting inside them. To get rid of the drugs that did get inside them, they produced pumps to blast them back out. Meanwhile, the entire microbiome powered down its metabolism. This is probably a good strategy for enduring antibiotics, which typically attack the molecules that bacteria use to grow. As the bacteria shut down, they had a direct effect on their host: they stopped making vitamins and carrying out other metabolic tasks.
When You Swallow A Grenade
In the poor, remote island nations of the South Pacific, the Type-II diabetes rate ranges from 19% to 34%, a devastating health statistic that is challenging the countries’ economies and wellbeing.
Deflazacort, a steroid, can be purchased online from non-US sources for $1.00, but now it’s being marketed by Illinois’s Marathon Pharmaceuticals for $89,000 as Emflaza, to treat Duchenne muscular dystrophy, which predominantly affects men in their 20s.
The best part of the video is the increasing happiness and confidence you can see on his face as his body transforms. (Isou Dw)
Python is immensely popular in the data science world for the same reason it is in most other areas of computing—it has highly readable syntax and is suitable for anything from short scripts to massive web services. One of its most exciting, newest applications, however, is in machine learning. You can dive into this booming […]
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Instead of throwing out all the empties after your next party, why not transform them into some new DIY glassware? Cut back on waste and add some home ambiance with the Kinkajou Bottle Cutter and Candle Making Kit.The Kinkajou is designed as a clamp-on scoring blade to make precise cuts. Just slide a bottle in, tighten […]