A quick Google reveals that this piece was known as (or was part of) "The Industry Series," an oil on board illustration (24" x 36") which was at one point owned by the Estate of Charles Martignette.
Who could she have been talking to? I have one idea.
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Boing Boing editor/partner and tech culture journalist Xeni Jardin hosts and produces Boing Boing's in-flight TV channel on Virgin America airlines (#10 on the dial), and writes about living with breast cancer. Diagnosed in 2011. @xeni on Twitter. email: email@example.com.