California baby is said to be first to be born with genome fully sequenced


In MIT Technology review, a feature about how an infant delivered last week in California is believed to be the first healthy human born in the USA "with his entire genetic makeup deciphered in advance."

The baby boy's father, Razib Khan, is a grad student, conservative blogger, and geneticist who says he "worked out a rough draft of his son’s genome early this year in a do-it-yourself fashion after managing to obtain a tissue sample from the placenta of the unborn baby during the second trimester."

“We did a work-around,” says Khan, 37, who is now finishing a PhD in feline population genetics at the University of California, Davis. “There is no map for doing this, and there’s no checklist.”

The idea of sequencing fetuses is extremely new and sensitive. Khan, who had no real medical reason to learn his son’s DNA code, says sequencing his son in utero “was more cool than practical.” He did it to show where technology is headed and because he likes “pushing the envelope.”

Khan is already well known in genetics circles as a conservative blogger who publishes provocative views on genetics, race, and reproduction, most recently at the Unz Review, and has also criticized government regulation of DNA testing. Among his most frequent predictions over the last few years: sequencing of fetuses will soon become routine, like it or not. “The future is here, deal with it,” he wrote on his blog in May.

Read the full feature here.