A large-scale, rigorous study published in the Lancet found that the go-to, front-line treatment for back pain was no better than a placebo.
We did a multicentre, double-dummy, randomised, placebo controlled trial across 235 primary care centres in Sydney, Australia, from Nov 11, 2009, to March 5, 2013. We randomly allocated patients with acute low-back pain in a 1:1:1 ratio to receive up to 4 weeks of regular doses of paracetamol (three times per day; equivalent to 3990 mg paracetamol per day), as-needed doses of paracetamol (taken when needed for pain relief; maximum 4000 mg paracetamol per day), or placebo. Randomisation was done according to a centralised randomisation schedule prepared by a researcher who was not involved in patient recruitment or data collection. Patients and staff at all sites were masked to treatment allocation. All participants received best-evidence advice and were followed up for 3 months. The primary outcome was time until recovery from low-back pain, with recovery defined as a pain score of 0 or 1 (on a 0—10 pain scale) sustained for 7 consecutive days. All data were analysed by intention to treat. This study is registered with the Australian and New Zealand Clinical Trial Registry, number ACTN 12609000966291.
Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial [Dr Christopher M Williams PhD, Prof Christopher G Maher PhD, Prof Jane Latimer, Prof Andrew J McLachlan PhD, Mark J Hancock PhD c, Prof Richard O Day MD, Chung-Wei Christine Lin PhD/The Lancet]
(Image: Hydrocodone, Guian Bolisay, CC-BY-SA)
Researchers at UC Riverside and Centro de Investigación Científica y de Educación Superior de Ensenada have published a paper describing their ongoing success in setting a “transparent nanocrystalline yttria-stabilized-zirconia” into patients’ skulls, which reveal the patients’ brains so that the patients’ brains can be zapped with therapeutic lasers.
One million miles from Earth, hanging in space between Earth’s gravitational pull and the sun’s, is the DSCOVR satellite and NASA’s incredible EPIC camera. Every two hours, EPIC takes a photo of Earth “to monitor ozone and aerosol levels in Earth’s atmosphere, cloud height, vegetation properties and the ultraviolet reflectivity of Earth.” The above video […]
In Botswana, conservation scientists from the University of New South Wales are painting eyes on the rear ends of cattle in an effort to deter lions from eating them. As the lions’ protected habitats shrink, they move closer to human settlements. In Botswana, the lions attack the livestock that the subsistence farmers count on. That […]
Home audio has taken some big leaps forward in recent years–not just in terms of sound quality, but also in the style department. The FRESHeBAR Leather Soundbar, now 56% off in the Boing Boing Store, is proof.The FRESHeBAR comes packing almost all the options you’d ever need for a home sound system, including Bluetooth streaming capabilities.The unit’s 90 […]
Much of what goes into creating an amazing photo happens in the digital darkroom. Here’s your chance to master all things photo editing: the Ultimate Adobe Photo Editing Bundle, now available in the Boing Boing Store for just $29.99.Across 8 courses and over 41 hours of intensive instruction, you’ll learn the fundamentals of Adobe’s suite of photo […]
3D printers are hot, but they’re also pricey. While the prospect of cranking out everything we can dream up is enticing, cost is often one factor that keeps us from jumping onto the 3D printing train.Now, thanks to M3D, that doesn’t have to be the case. You can now get its flagship 3D printer–plus four reels of filaments–for just […]