Vietnamese gentleman Thái Ngọc claims that ever since he suffered a terrible fever in 1973, he hasn't slept a wink. There's also Ines Fernandez who says she's been awake for decades. Of course, these curious individuals and others with similar stories may actually be suffering from a very strange sleep disorder called sleep state misperception (SSM) in which the individuals think they were up all night but actually slept just fine. At Mysterious Universe, Martin J. Clemens looks at SSM and the very scary rare disease called Fatal Familial Insomnia (FFI), presented as total insomnia that can last the rest of the person's life, which is usually only 18 months or so after the onset of symptoms. From Mysterious Universe:
FFI is a neurological condition caused by a misfolded protein in the DNA of the afflicted, of which there have been only about 100 cases. That protein, called a prion protein, is known as PrPSc (PrPC in non-FFI subjects). Essentially, the prion form of the protein causes a change in certain amino acids – due to the protein strand folding incorrectly – which, when combined with other genetic markers, then affects the brain’s sleep centers. FFI is genetic, and therefore hereditary, but there is an even rarer form known as Sporadic Fatal Insomnia (sFI) that occurs spontaneously, the cause of which is not understood. You may wish to know that PrPSc is the same protein that’s responsible for bovine spongiform encephalopathy, also known as Mad Cow Disease.
"The Woman Who Stayed Awake for 30 Years…Or Did She?
Rolling Stone’s Mac McClelland tells the story of the physicians bravely breaking the law by treating patients with MDMA, ayahuasca, DMT, LSD, and other hallucinogens. From RS: As an internal-medicine specialist, Dr. X doesn’t have any patients who come to him seeking psychotherapy. But the longer he does the work, the more “I’m seeing that […]
Lots of people think they’re allergic to penicillin, but aren’t — so when they have infections, doctors are obliged to skip the front-line drugs, which accelerates the pace of antibiotic resistance in common bacteria.
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When you can’t wait for the world’s longest meeting to end, the mindless leg bouncing makes your boredom obvious and just annoys everybody else. Everyone knows the TPS reports need the damn cover sheet, but some sadistic colleague keeps forgetting, probably on purpose just to eat into your lunch hour. Enough is enough!While serving a […]
What could be more fun than a slingshot that shoots tiny airplanes? A slingshot that shoots tiny glowing airplanes of course! These toy planes are outfitted with ultra-bright LEDs, so you can fly all night without losing them in the trees.Whether you are a regular-sized child, or an overgrown adult one, these light-up flyers offer […]
You know the drill. You go to the dentist and they ask you how often you floss. You lie through your teeth and say, “every day!” (Bonus points if you have some cilantro or chives stuck in your gums from lunch). You don’t want to keep up the charade any longer, but rubbing that tiny strand […]