According to the Minneapolis Star-Tribune, Prince died the day before he was to meet with a California physician who specializes in opioid addiction:
Dr. Howard Kornfeld, a national authority on opioid addiction treatment, was called by Prince representatives the night of April 20 because Prince “was dealing with a grave medical emergency,” said William Mauzy, a prominent Minneapolis attorney working with the Kornfeld family.
Kornfeld, who runs Recovery Without Walls in Mill Valley, Calif., could not clear his schedule to meet with Prince the next day, April 21, but he planned to fly out the following day.
So he sent his son, Andrew Kornfeld, who works with him, to Minnesota, with plans for him to go to Paisley Park to explain how the confidential treatment would work, Mauzy said...
When Andrew Kornfeld arrived at Paisley Park at 9:30 a.m. Thursday, Prince’s representatives could not find him, Mauzy said. Andrew Kornfeld was one of three people at Paisley Park when the musician’s body was found in an elevator a few minutes later — and it was Andrew Kornfeld who called 911
Pakistan's daily news service Dawn reports on the rise in scorpion smoking there:
Here is a startlingly compelling implementation of the classic Windows Solitaire victory animation: simply click and win! The creator is Richard Cabello, who has perhaps played enough Windows Solitaire for one lifetime. Read the rest
On the science of alcohol and alcholism, from 1949, Encyclopedia Brittanica films. Booze: “a potential menace to community safety as well as personal health”.
Pre-gaming didn't have a name when I was their age; it's interesting how the phenomenon (is it even a phenomenon?) has become a media meme this year. This NYT story is another example.
I realize the newly-released study provides citeable evidence about a behavior with dangerous consequences, but the results are kind of like, yo, thanks, Captain Obvious.
"Increased drinking was associated with a greater likelihood of blackouts, hangovers, absences from work or school or alcohol poisoning. Pre-drinkers were also found to engage more often in unintended drug use, unsafe sex, drunken driving or violent behavior."
We recently hosted an article by scientist and guest blogger Stephan Guyenet that explained how certain foods—those with a high calorie density, fat, starch, sugar, salt, free glutamate (umami), certain textures (easily chewed, soft or crunchy, solid fat), certain flavors, an absence of bitterness, food variety, and drugs such as alcohol and caffeine—could trip reward systems in the human brain. Those reward systems, then, encourage people to eat more of the foods that trigger the reward. The result, says Guyenet, is a cycle that could be the link between the American obesity epidemic and the rise of highly processed convenience foods, designed specifically to trip those neural reward systems.
This theory, and several related theories, are increasingly popular in the scientific community. This week, there's an opinion piece in the journal Nature Reviews Neuroscience that looks at the strengths and weaknesses of these theories and talks about what research needs to be done going forward. It's kind of a space for researchers to step back and say, "Okay, here's what we know, here's what's not lining up with what we think we know, and here's what we have to do if we want to understand this better." In the context of science, an article like this isn't really a slam against the ideas it analyzes. Instead, it's meant to summarize the state of the science and share ideas that could either strengthen the case, or lead down entirely new roads.
Sadly, you can't read this article unless you have a subscription to Nature Reviews Neuroscience (or pay them $32 for single article access). Read the rest
Dopamine does a lot of things, but you're probably most familiar with it as the chemical your brain uses as a sort-of system of in-game gold coins. You earn the reward for certain behaviors, usually "lizard-brain" type stuff—eating a bowl of pudding, for instance, or finally making out with that cute person you've had your eye on. And, as you've probably heard, there's some evidence that we can get addicted to that burst of dopamine, and that's how a nice dessert or an enjoyable crush turns into something like compulsive eating or sex addiction.
Neurologist Robert Sapolsky puts an interesting twist on this old story, though. What if it isn't the burst of dopamine that we get addicted to, but the anticipation of a burst of dopamine? It's a small distinction. But it matters, he says, if our reward system is based less on happiness than on the pursuit of happiness.