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TV, video games, or Internet: Which activity makes teenagers fat?

I talk a lot about the importance of context in understanding science. The results of one, single research paper do not tell you everything you need to know on a given subject. Instead, you have to look at how those results fit into the big picture. How do they compare to the results of other studies on the same subject? Have the results been independently verified? How do the specific experiments being done influence what you can and cannot say about the results? What questions aren't answered by the study, and what new questions does it bring up?

You should be thinking about that every time you see anybody talk about the results of a single, new study. Without context, you get situations like this one, described by Travis Saunders on the Obesity Panacea blog:

Earlier this year my friend and colleague Valerie Carson published an interesting paper examining the health impact of various types of sedentary behaviour in a sample of 2500 children and adolescents. They created a clustered risk score (CRS) which took into account a child’s waist circumference, blood pressure, cholesterol, and inflammation, and then examined whether it was associated with 3 different measures of sedentary behaviour – accelerometry (an objective measure of movement), self-reported TV watching, and self-reported computer use.

Here is what they found (emphasis mine): For types of sedentary behavior, high TV use, but not high computer use, was a predictor of high CRS after adjustment for MVPA and other confounders. Here is what the Daily Mail had to say: Watching TV most damaging pastime for inactive children, increasing risk of heart disease.

Last month, our group in Ottawa published another paper (led by Dr Gary Goldfield) looking at different types of sedentary behaviour and heart disease risk factors in a cohort of overweight and obese teens (in contrast, the earlier study was on a sample of nationally representative youth). Interestingly, we found that neither TV time nor computer time was associated with increased risk in this group - in our dataset it was video games that were by far the most important sedentary behaviour.

Why is this a problem? Put yourself in the shoes of someone who just read the Daily Mail article, and who now believes that TV viewing is the single most damaging sedentary behaviour for kids to engage in. What reaction are you going to have when you read a similar article about our new study, suggesting that TV viewing and computer use aren’t important at all, but that video games are actually “the most damaging activity an inactive child can indulge in”?

As the source of this problem, Saunders rightly calls out journalists for pushing every individual study as a "GROUNDBREAKING NEW FINDING". It is, unfortunately, rare to find TV and newspaper coverage that treats new studies in context, rather than as the final word. But to that, I'd add university PR people. The sad truth is, with newspaper layoffs, many of the people writing about science aren't specialists. They cover city council one day, school board the next, and a new research finding after that. The press releases they get (and I know, because I get those press releases, too) push GROUNDBREAKING NEW FINDINGS not research that fits into a larger context. It's the journalists job to know better. But it's also the university's job to not manipulate journalists.

Faster-than-light neutrino update: What's going on behind the scenes?

The publication process for a research paper about physics works a little differently than other subjects. That's because of arXiv. Funded by Cornell University, this site posts research papers, before they're formally published in a scientific journal. Unlike most scientific journals, which charge big fees for subscriptions or even to view a single paper, arXiv is free and open to the public. You can read everything published there—more than 700,000 papers about physics, math, computer science, and more. The other big difference: arXiv isn't peer reviewed. At least, not ahead of time.

A lot of the time, when you read a newspaper article about a new study in one of those fields, the study hasn't actually yet been published in a peer-reviewed journal. It's just been posted to arXiv, which sort of becomes a crowd-sourced peer review peer review of its own. Especially for headline-grabbing research making big, bold claims.

That's the background you need to understand what's going on right now with the study that claimed to find neutrinos traveling faster than the speed of light. That announcement was made in an arXiv paper. Putting those results on arXiv was as much a way of saying, "Woah, we just found something crazy, please tell us if you see something we've done wrong," as it was a formal declaration of scientific discovery.

Since that paper was published in September, there have been more than 80 follow-up papers, also published on arXiv, offering criticism of the original research or proposing theoretical explanations of how that seemingly crazy finding could fit into physics as we know it. And all of this is happening before anybody has gone through the peer-review publishing process.

That's why it's not terribly weird that you're now hearing all sorts of criticism of the original FTL neutrino findings. That's what was supposed to happen. It's also not terribly weird that the original researchers have announced that they're going to re-do the experiment themselves, taking into account some of the big criticisms brought up on arXiv. The BBC explains what will be done differently this time:

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Caffeine hallucinations: Why "Letters to the Editor" matter in science

Letters to the Editor are an interesting feature of peer-reviewed scientific journals. The function of this section varies from journal to journal, but, in general, this is where you'll find things like critiques of research published in previous issues, and short write-ups on findings that don't yet warrant their own big, formal research paper. Neuroscience blogger Vaughan Bell found a neat example of the latter in an old 1993 issue of the American Journal of Psychiatry.

Dr. Harold W. Koenigsberg and his colleagues were in the process of studying the causes of panic and anxiety disorders, in hopes of better understanding why some people are prone to panic attacks and others aren't. Part of that research involved determining whether you could have a panic attack while sleeping. They wanted to see whether a panic attack could still happen if the patient wasn't actively thinking about the causes of the panic attack, like they might when awake. Basically, Koenigsberg was trying to figure out how much of a panic attack was attributable to chemistry changes, and how much was related to cognitive processing.

Koenigsberg and company injected sleeping patients with caffeine, to produce the physical symptoms of panic. And that's when they noticed something odd. Two of the patients reported olfactory hallucinations—they smelled things that weren't there. Here's what Koenigsberg wrote in his Letter to the Editor:

Mr. A, a 38-year-old man with no personal or family history of psychiatric disorders, received an intravenous dose of 250 mg of caffeine, delivered as a bolus over a 60-second period during an episode of stage 3-4 sleep. Fourteen minutes after receiving the caffeine, he awakened and reported an “interesting smell or taste-more like a smell.”

Ms. B, a 34-year-old woman with a generalized anxiety disorder, awakened experiencing a smell like that of “plastic or burnt coffee” 3 minutes after receiving a 250 mg bolus of caffeine during a period of stage 3-4 sleep.

Previous research by other people had found that hallucinations like this could happen, but the hypothesis had been that the hallucinations were related to seizures. Koenigsberg's patients had no history of seizures, and they hadn't shown any signs of experiencing seizures when they had their hallucinations.

So Koenigsberg offered a new hypothesis: We know caffeine can work as a taste enhancer. So, maybe, the intravenous caffeine was either causing people to pick up smells and tastes that were normally undetectable, or the caffeine was prompting sensory systems to trick themselves, finding "smells" where none actually existed.

And this is why Letters to the Editor are so nifty. Koenigsberg later published on his panic attack study, but the biochemical function of caffeine on the human sensory system wasn't something he was much interested in. Letters to the Editor allowed him to share a weird finding, which might otherwise have been shoved into a drawer, never to be heard from again.

Instead of being lost, Koenigsberg's finding on caffeine-induced hallucinations went on to influence at least four other studies, including one on migraine hallucinations published last month.

Image: Caffeine fix, a Creative Commons Attribution (2.0)image from davemorris's photostream

Sunset on the Tevatron: Photos and memories from a Fermilab physicist

For more than 20 years, the Tevatron reigned as the gold standard in particle accelerators. Under a berm outside Batavia, Illinois, the machine pushed protons and antiprotons to high energies around circular tracks before crashing them into each other. What's the point of that? When high-energy protons and antiprotons collide, they reproduce the conditions at the beginning of the Universe, just after the Big Bang. In the wreckage, you can find particles that don't normally exist, and observe phenomena that humans have never seen before. By rubbernecking at a particle crash, researchers hope to better understand life, the Universe, and everything. It's kind of a big deal.

But on Friday, September 30, the Tevatron smashed its last protons.

Ultimately, the Tevatron was simply the victim of the progress of technology. When it opened in 1983, it replaced older, lower-energy accelerators. And, in turn, the Tevatron has been replaced by the Large Hadron Collider, an accelerator capable of pushing particles to even higher energies. Once that happened, it was only a matter of time before the Tevatron felt the budgetary axe.

The end of the Tevatron doesn't mean the end of research at the Fermi National Accelerator Laboratory, and it doesn't mean the end of particle research in the United States. But it is the end of an era.

William S. Higgins is a radiation safety physicist at Fermilab, and a contributor to Tor.com. He helped build the Tevatron and he was on hand last Friday, recording his thoughts and some photos to share with us. Here, you'll find a sentimental scientific tour of the last day of a great piece of research equipment. Unless otherwise noted, all the captions were written by Higgins.

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Inside Alvin: Scientists as Makers

There are things you can't buy at Radioshack. There is not always an App for that. Sometimes, the only way to make something work is to build it yourself.

Nobody knows that better than scientists.

From physicists tracking a particle, to taxonomists identifying a new species of wasp, to chemists creating a useful molecule—nearly every discovery you read about in the paper began with the researchers creating the tools they needed to test their own hypotheses. In the lab, DIY isn't just a hobby. It's part of the job.

And Alvin, a research submersible owned by the U.S. Navy and operated by the Woods Hole Oceanographic Institute, is one of the most successful scientist DIY projects ever. Launched in 1964, Alvin was part of a trend. At the time, everybody wanted their own deep-sea-worthy mini-submarine. But, almost 50 years later, Alvin is one of the few still in use. The little research vessel that could, Alvin was made—and is regularly re-made—by the very people who use it.

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How beautiful space photos are made

The Hubble Space Telescope doesn't just produce glossy, full-color posters on its own. It takes a little work to get from raw images to the photos we gawk over on the Internet. This video takes you through the process of turning three different black and white images into one complete, beautiful photo of a spiral galaxy.

Video Link

More info on the official Hubble site

Via Sheril Kirschenbaum

Lucky Cosmonaut

Everybody say, "Hello," to Russian cosmonaut Yury Malenchenko. Hi, Yury!

I like this photo because he kind of reminds me of one of those Japanese lucky cats.

Image: REUTERS/Sergei Remezov

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