PUMP, or Problematic Use of Mobile Phone, happens when users turn to their phones instead of in-person contact to alleviate depression, according to a new study in Computers in Human Behavior. Read the rest
In a heartfelt and frank interview (conducted by our own Caroline Siede!), Wil Wheaton discusses the moment he realized he needed help with his clinical depression, and the moment he realized that the help was helping. Read the rest
Ketamine, a tranquilizer/anesthetic and recreational drug, can relieve symptoms of depression for up to a couple of weeks, writes psychiatrist Emily Deans.
The Ketamine Key: The horse tranquilizer helps depressed patients experience pleasure again Read the rest
In a recent paper, researchers described how they used a noncompetitive inhibitor of the NMDA receptor and partial dopamine receptor agonist, ketamine to rapidly reverse the symptoms of anhedonia in depressed patients. Ketamine has been featured on CBS news for its ability to quickly relieve depression unlike any other pharmacologic agent we have. It is typically used intravenously, and can cause hallucinations and dissociation (in fact it is also known as the club drug “Special K"). However, it seems to be able to reverse damage to the synapses caused by chronic stress, and relieve the symptoms of depression very quickly, within 30-40 minutes.
The down side to ketamine (besides lack of FDA approval for depression, the hallucinations, and lack of general availability) is that the effects don’t last. If you are lucky, you get a couple of weeks, then the depression comes back. Researchers and doctors, however, are hoping ketamine could be used as a bridging agent in seriously depressed, hospitalized patients, allowing them to feel better immediately while other, longer acting but much slower onset agents have a chance to get into the system and do their work. The immediate reversal of the key symptom of anhedonia [inability to experience pleasure] may be an even more important lesson we can learn from the use of ketamine.
"I'm sure most of you have heard the story of the man who, desperately ill, goes to an analyst and tells the doctor that he has lost his desire to live and that he is seriously considering suicide. Read the rest
Miss Cakehead writes, "The Depressed Cake Shop will be like nothing ever seen before as it will sell ONLY grey coloured cakes. Raising money for mental health charities, it will also provide a platform for discussion of the illness. The pop up is based in the UK but with other events starting to be planned around the globe."
Suicide is not hard to understand, not intellectually anyway. It is, as Jeff Atwood says, the ultimate in ragequitting. But for most of us, it is hard to understand emotionally.
For a variety of reasons, I’ve spent a lot of time with people at risk of suicide, and so have become an amateur scholar of that choice. When I first started reading about it, I thought of it as the last stop on a road of stress and upset — when things get bad, people suffer, and when they get really bad, they take their own lives.
And what I learned was that this view is wrong. Suicide is no more a heightened reaction to the slings and arrows of outrageous fortune than depression is just being extra sad. Most of us won’t kill ourselves, no matter how bad things get. The common thread among people who commit suicide is that they are suicidal.
Hyperbole and a Half, the brilliant, frenetic, illustrated memoir, tackles sudden depression, its effects and eventual cure in the long awaited new installment.
I spent months shut in my house, surfing the internet on top of a pile of my own dirty laundry which I set on the couch for "just a second" because I experienced a sudden moment of apathy on my way to the washer and couldn't continue. And then, two weeks later, I still hadn't completed that journey. But who cares - it wasn't like I had been showering regularly and sitting on a pile of clothes isn't necessarily uncomfortable. But even if it was, I couldn't feel anything through the self hatred anyway, so it didn't matter. JUST LIKE EVERYTHING ELSE.