At PBS NewsHour, Jenny Marder has a truly epic report on so-called "bath salts," a term commonly used to refer to a variable cocktail of drugs linked to a number of violent episodes throughout the US. Her investigative feauture is the most extensive and authoritative I've seen on the topic, a long read full of the stuff that makes great reporting great: nitty-gritty chemistry mysteries, personal stories about the people who use the drug, and big-picture questions about why the stuff is so widely available, and why it seems to be so destructive. Don't miss the slide shows and video that accompany the beautifully laid-out feature. There's even an instructional animated gif!
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Users are often hyper-agitated, hot and sweating, she said. Their heart rate is dangerously high, their blood pressure is up, and seizures are common. Often even high doses of common sedatives don't help them. Doctors instead must turn to antipsychotics or other powerful medications.
Early on, doctors began noticing something else that was strange. Compared with other drugs, bath salts didn't follow a normal dose-response pattern. With cocaine or methamphetamine, the drug entered the bloodstream, and, within hours, began to wear off. Not so for bath salts. “Some patients were in the hospital for 5 days, 10 days, 14 days,” Ryan said. “In some cases, they were under heavy sedation. As you try to taper off the sedation, the paranoia came back and the delusions."
As Ryan was scrambling to grasp the scope of the problem in Louisiana, scientists 1,000 miles away were beginning to tease out the drug's chemistry.