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The trial of a 14th century female doctor

In November 1322, Jakoba (or Jacoba) Felicie stood trial in her native Paris for the crime of practicing medicine without official sanction. Over the course of the trial, it became clear that her work as a doctor had been excellent. But Dr. Felicie was stuck in an unfortunate catch-22. She could not legally work as a doctor without first getting professional training. And she could not get professional training because she was a woman. The ScienceZest blog tells her story. Maggie

Drug OD fatalities up for 11th consecutive year; not one was due to marijuana

Federal data to be released this week through the Journal of the American Medical Association shows that drug overdose deaths rose for the 11th year in a row. Most were accidents involving prescription painkillers: specifically, opioids like OxyContin and Vicodin which are commonly prescribed for pain management, and are widely abused. Those two drugs contributed to 3 out of 4 medication overdose deaths, according to the report.

Not one single death in the Centers for Disease Control and Prevention data set was due to overdosing on marijuana.

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Vaccine-resistant whooping cough found in Philadelphia

When we talk about the resurgence of childhood illnesses, we tend to focus on vaccine-resistant people as the primary cause. And it's true that a large population of un-vaccinated kids can give a disease like whooping cough a foothold in a community, and allow it to spread to kids who haven't been vaccinated yet or who can't be vaccinated for various medical reasons. But there's another facet to this story, as well. Some of the strains of bacteria that cause whooping cough are also resistant to the vaccine. Those strains have been found in Japan, France, and Finland. Last week, The New England Journal of Medicine reported on 12 cases of vaccine-resistant whooping cough in Philadelphia. Maggie

Medical cures from the mouth of a mamba

Here, scientists suck all the dignity out of a Jameson’s mamba — a snake capable of killing a human in just a few, painful hours. The photo is part of a story in the February issue of National Geographic, exploring the potential medical uses of venom. There are also more photos. And you will meet cobra farmers.

© Mattias Klum /National Geographic

Medicine or moralism: A psychotherapist questions "sex addiction"

Can you actually be addicted to sex? Marty Klein doesn't think so. In an interesting article at The Humanist, he critiques the diagnostic criteria and common treatments behind this tabloid-ready psychological problem. Maggie

Forget scarlet fever: What really blinded Mary Ingalls

Anybody who has spent much time with children's literature knows that scarlet fever blinded Mary Ingalls.

But scarlet fever doesn't cause blindness.

Mary really did become blind, though, in real life as well as in the books, so what was the real culprit? A paper published this week in the journal Pediatrics speculates that it could have been viral meningoencephalitis — inflammation in the brain and in the membranes that surround the central nervous system.

There are several possible causes. In Europe and Asia, ticks can spread a virus that causes meningoencephalitis. West Nile virus can cause it, as well. So can the mumps. And so can herpes simplex type 1 — the oral herpes virus that is present in the vast majority of people.

Which means that this story not only has ties to the other Little House history pieces we've run here at Boing Boing — the meteorology of the Long Winter, and the crazy connection between the Ingalls' and a family of serial killers — it's also, possibly, another example of a heroine from children's fiction who had herpes.

The full paper, sadly, is behind a paywall. But The New York Times' Motherlode blog has a nice summary of it.

Image: Wikipedia editor Lrcg2012, via CC

The role of anecdotes in science

Anecdotes aren't data — but they do make data memorable. Maggie

Anne of Green Gables had herpes (and you probably do, too)

From Chapter 40 of Anne of Ingleside:

Anne sneezed. She began to be afraid she was taking a cold in the head. How ghastly it would be to sniffle all through dinner under the eyes of Mrs. Andrew Dawson, nee Christine Stuart! A spot on her lip stung . . . probably a horrible cold-sore was coming on it. Did Juliet ever sneeze? Fancy Portia with chilblains! Or Argive Helen hiccoughing! Or Cleopatra with corns!

Yes, Anne of Green Gables, by the time she reached middle-age, had apparently joined the majority of adults who test positive for the virus herpes simplex type 1 — the cause of the painful, little mouth blisters known colloquially as "cold sores". Estimates vary when it comes to how many of us are HSV-1 carriers. A 2006 study found evidence of HSV-1 infection in 57.7 percent of American adults, ages 14 to 49.* Bryan Cullen, a virologist at Duke University, told me he's seen studies showing that closer to 70 percent of adults are infected — although only something like 1/3rd of those will ever get cold sores.

Don't judge Anne of Green Gables. Chances are good that you're in the same boat.

But why is this virus so common?

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What it's like to have a grand mal seizure

Radio producer Jess Hill, who has been working in the Middle East, wrote an account of what the experience of having a grand mal seizure was like.

She wrote the post a week after the episode, and two weeks before having brain surgery to remove the tumor that caused it.

"At the time I was still having seizures every few days, and just the act of writing about the first seizure in such detail almost brought on another one," Jess explains. "I initially planned to keep this account private, but after two months, I’ve decided to share it, if only for the fact that it might be useful to others who have had or will have a similar experience."

It happened when she was in transit via plane from Yemen to Beirut.

Read the rest

The science of flu season

Flu season is in winter. Okay, great. But why? (Consider this an open thread for all your favorite humidifier recommendations.) Maggie

An epidemiology alphabet

The only alphabet guaranteed to make you want to wash your hands. Made by one, Jennifer Gardy.

In related news, this video taught me that the parasite giardia is sometimes called "beaver fever". Why? Because one of its major reservoirs — species that can comfortably host a parasite and pass it on to others — is, yes, the beaver.

Now here's the part you probably don't want to hear. Giardia is transmitted via what's known as the "fecal-oral route".

Now, nobody intentionally goes out and eats beaver shit. (One hopes. But this is the internet.) But beavers do shit in the woods. Near woodland streams. Which means that unwary hikers and backpackers can end up ingesting giardia when they drink from what appears to be crystal-clear waters.

Via the Worms and Germs blog

The protective power of antioxidants might be vastly oversold

Scientists are beginning to question the idea that free-radicals cause aging and, with that, the entire basis of the antioxidant industrial complex. Maybe, now, everything can stop tasting of acai berries. Maggie

FDA wants Ambien doses cut for women because users are crashing cars the morning after

The Food and Drug Administration today announced it will require the makers of popular sleeping pills like Ambien and Zolpimist to reduce the recommended dosage in half for women, "after laboratory studies showed that the medicines can leave patients drowsy in the morning and at risk for car accidents." Women eliminate the drugs from their bodies more slowly than men. (NYT) Xeni

Another danger for astronauts: Super bacteria

Bacteria living zero-gravity environments become more virulent. People living in zero-gravity environments have less-than-fully-functional immune systems. The result is a danger for space travelers that few of us on Earth ever think about — even though a lot of early astronauts, right up through the Apollo program, suffered severe infections in flight, or shortly after landing. Ed Yong's article for Wired UK from 2011 is a reminder that there's a lot of details that need to be worked out before humanity can become a space-faring species. We've got more worry about up there than just radiation. Maggie

Creepy long-read on the science of surgery patients who wake up during anesthesia

I have breast cancer, and I am going in for more surgery tomorrow. Awakening, by Joshua Lang in The Atlantic, may not have been the best choice for pre-op reading material, but it is a fascinating piece. Read at your own peril if you're planning on a trip to the O.R. any time soon. The tl;dr: tens of thousands of patients each year in the US slip out of anesthesia and regain wakeful consciousness during surgery. They can't alert anyone, and they suffer PTSD in high rates. What does it mean to be conscious? And how can this phenomenon be prevented?

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