Antibiotic resistance is older than antibiotics

This came out while I was traveling, but I wanted to post it here in case you missed it. It is very cool, in that "maybe cool isn't the right word" sort of way. Our modern antibiotics are really just purified and pumped-up versions of naturally occurring compounds, right? So, it makes sense that, long before we started using them as antibiotics, bacteria had already started building defenses against the natural compounds. In other words: Antibiotic resistance is older than the use of antibiotics.