Thinkgeek's Werewolf Zombie Trophy ($35) is made from hand-painted resin and is 5.5"x7.5"x4.5" -- just the thing for showing off your monster-slaying prowess. I mean, anyone can kill a zombie. Or a werewolf. But a werewolf zombie? That's some shootin', Tex. Read the rest
The Scrubba is a washtub, washboard, soaker and dry-rack that collapses down and fits in your pocket, and can also serve as a drybag for camping trips. Read the rest
Ketamine, a tranquilizer/anesthetic and recreational drug, can relieve symptoms of depression for up to a couple of weeks, writes psychiatrist Emily Deans.
In a recent paper, researchers described how they used a noncompetitive inhibitor of the NMDA receptor and partial dopamine receptor agonist, ketamine to rapidly reverse the symptoms of anhedonia in depressed patients. Ketamine has been featured on CBS news for its ability to quickly relieve depression unlike any other pharmacologic agent we have. It is typically used intravenously, and can cause hallucinations and dissociation (in fact it is also known as the club drug “Special K"). However, it seems to be able to reverse damage to the synapses caused by chronic stress, and relieve the symptoms of depression very quickly, within 30-40 minutes.
The down side to ketamine (besides lack of FDA approval for depression, the hallucinations, and lack of general availability) is that the effects don’t last. If you are lucky, you get a couple of weeks, then the depression comes back. Researchers and doctors, however, are hoping ketamine could be used as a bridging agent in seriously depressed, hospitalized patients, allowing them to feel better immediately while other, longer acting but much slower onset agents have a chance to get into the system and do their work. The immediate reversal of the key symptom of anhedonia [inability to experience pleasure] may be an even more important lesson we can learn from the use of ketamine.
The Ketamine Key: The horse tranquilizer helps depressed patients experience pleasure again Read the rest
Carrying on the sleazy tradition of professional liar Harry J. Anslinger (first commissioner of the U.S. Treasury Department's Federal Bureau of Narcotics), weed prohibitionists are stretching the truth and outright fibbing in a desperate attempt to reverse the nationwide trend towards legalization. Read the rest
A woman working at a convenience store calmly sprayed aerosol insecticide at a masked robber who, in turn, calmly walked away. Read the rest
a 1955 Chevy Nomad wagon. 'It has completely original paint, interior, and drive train,' Pinchot says, 'and is so clean, I thought for sure it was a restored car until I saw it in person.' The two-door station wagon, which has been kept safe and warm in storage since 1974, has 87,000 original miles on it, and Pinchot is only its second or third owner, 'depending on if you count the original owner’s son, who inherited the car.'”
Ben Marks of Collectors Weekly says: "Justin Pinchot just sent us a video of his new pride and joy,
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Meet Maddie, one of the best unrestored, original paint & interior examples known of the rare & iconic 1955 Belair Nomad wagon. Out of nearly a million Chevy Belairs built in 1955, only about 8100 Nomads were ever produced; this example is in the most desirable regal turquoise with India ivory top. First year of Chevy's small block V8, the 265, it is mated to a 2-speed cast iron powerglide automatic transmission. All mechanical components are original to the car as it left the factory. All 55 Nomad bodies were produced at the Cleveland plant then assembled & finished at various plants around the country; this one in Oakland California. Born Aug. 15, 1955, it is one of the last 55 Nomads off the assembly line before production switched over to the 56 model in September of that year. In astonishingly clean condition, Maddie will turn 60 years old this coming year. She looks pretty damn good for an old girl.
Said no one, ever. Except, apparently not: the "data scientists" of Posterscope are excited that EE -- a joint venture of T-Mobile and Orange -- will spy on all their users' mobile data to "give profound insights...that were never possible before" Read the rest
Of course, artists have been taking selfies for centuries, but Zinaida Serebriakova was one of the best. Read the rest
Matt and Shannon Cyphert of MTP Studios introduce us to the sport, art, and people of windless kite flying in this beautiful trailer. Read the rest
By Lyon, France-based artist Me & Edward. “ Just like a chameleon, it’s fitting, just like a virus, it’s mutating, just like a personality, it’s changing.”
Lil Dicky is one of the funniest novelty song artists working today. His newest NSFW ode to modern manhood will ring true to both guys and those who have to endure guys' advances. Read the rest
What is GamerGate all about?
Noted. Thank you, New York 1 anchor Errol Morris. We'll just go back to eating the poop and snot of people who are Ebola-free. Read the rest
After the spectacular rise and fall of Anonabox, a kickstarted $45 router that was supposed to protect your privacy but had its campaign yanked for not being entirely forthright with backers, a spate of shady, silly, and even serious projects have sprung up to fill the demand that Anonabox's $615,000 Kickstarter near-win demonstrated. Read the rest
Photographer Pablo Moltedo has a lovely collection of macro photos like "Contraste" above, including some creepy crawlies if you want some pre-Halloween squickage. Below, a snail with a beautiful red and black shell. Read the rest