Genomic sequencing finds no single gene basis for extreme longevity

Misao-OkawaWhole genome sequencing has not found any single gene variation responsible for extreme longevity, according to a paper published in PLOS ONE:

We have sequenced the genomes of 17 supercentenarians (over 110 years of age) to see if we could uncover the genetic basis for their extreme longevity. We analyzed rare protein-altering variants, but found no strong evidence for enrichment of either a single variant or a single gene harboring different variants in female Caucasian supercentenarians compared to controls.

The full genomic sequences have been published, allowing other researchers to build on the data set.