In this video we meet Yutaka Sasaki, a chef who prepares fugu, a fish that contains a lethal neurotoxin called tetrodotoxin.
Fugu contains lethal amounts of the poison tetrodotoxin in its organs, especially the liver, the ovaries, and the eyes, whereas skin is usually non-poisonous. The poison, a sodium channel blocker, paralyzes the muscles while the victim stays fully conscious (thus making the effects somewhat similar to those of the nerve agents Sarin and VX); the poisoning victim is unable to breathe, and eventually dies from asphyxiation. Fugu poison is 1200 times stronger than cyanide, and there is no known antidote. The standard treatment is to support the respiratory and circulatory systems until the poison is metabolized and excreted by the victim's body. (Wikipedia)