Nature Magazine reports that researchers from Imperial College London gave psilocybin to 12 people with depression. All the patients showed "a marked improvement in their symptoms."
Researchers from Imperial College London gave 12 people psilocybin, the active component in magic mushrooms. All had been clinically depressed for a significant amount of time — on average 17.8 years. None of the patients had responded to standard medications, such as selective serotonin re-uptake inhibitors (SSRIs), or had electroconvulsive therapy.
One week after receiving an oral dose of psilocybin, all patients experienced a marked improvement in their symptoms. Three months on, five patients were in complete remission.
“That is pretty remarkable in the context of currently available treatments,” says Robin Carhart-Harris, a neuropsychopharmacologist at Imperial College London and first author of the latest study, which is published in The Lancet Psychiatry.
The equivalent remission rate for SSRIs is around 20%.
Pioneering psychonaut Ralph Metzner who co-led the seminal psychedelic research at Harvard University in the early 1960s with Timothy Leary and Richard Alpert (Ram Dass) and co-authored The Psychedelic Experience, has died at age 82. (Above image, Metzner at left with Leary.) Through his life, Metzner helped a great many people through his psychotherapist practice, […]
Earlier today, the FDA approved esketamine (brand name Spravato), a chemical twin of the dissociative psychedelic/anaesthetic ketamine (Special K), as a treatment for depression. Spravato comes in nasal spray form meant to be administered weekly or every other week depending on the severity of the patient’s depression. “There has been a longstanding need for additional […]
Based on a new study of the safety and abuse potential of psilocybin, the hallucinogenic drug in magic mushrooms, Johns Hopkins University School of Medicine researchers recommend that “psilocybin should be re-categorized from a schedule I drug—one with no known medical potential—to a schedule IV drug such as prescription sleep aids, but with tighter control.”
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