In 1943 Sandoz chemist Albert Hofmann became the first person to synthesize (and take) LSD. He was also the first person to isolate and identify psilocybin, the main psychedelic component in magic mushrooms, almost 60 years ago. "Yet no one has been able to unravel the enzymatic pathway the mushrooms use to make psilocybin, until now," reports Stephen K. Ritter of Chemical and Engineering News.
Janis Fricke, Felix Blei, and Dirk Hoffmeister of Friedrich Schiller University Jena have identified and characterized to the greatest extent so far the four enzymes that the mushrooms use to make psilocybin. The team then developed the first enzymatic synthesis of the compound, setting the stage for its possible commercial production (Angew. Chem. Int. Ed. 2017, DOI: 10.1002/anie.201705489).
Image: Erik Fenderson/Wikipedia
Oakland, California is now the second city in the United States, following Denver last month, to decriminalize psilocybin mushrooms. Oakland City Council unanimously passed the resolution on Tuesday. From NPR: Oakland’s resolution is broader than Denver’s. Denver’s initiative decriminalized the use and possession of mushrooms containing the compound psilocybin, whereas Oakland’s refers to “entheogenic plants” […]
This morning’s news reported that Denver’s ballot measure to decriminalize psychedelic mushrooms had failed, but now that all the ballots have been fully counted we’ve learned that the Sunnies outvoted the Sadsters 51% to 49%. From Forbes: Its provisions prohibit the city government from using any resources to impose criminal penalties against adults over 21 […]
In a Bolivian rock shelter likely used 1,000 years ago for religious rituals, archaeologists found a collection of drug paraphernalia that still contains traces of psychoactive plants. A pouch made from three fox snouts likely contained a stash of leaves and seeds. From New Scientist: (The items) include a 28-centimetre-long leather bag, a pair of […]
With the rising temperatures on tap this summer, the climate is going to be a frequent topic of conversation, and those conversations won’t be happy ones. Luckily, there’s a way to do a little climate change of your own – in a safe and sustainable way. When it comes to personal air conditioners, EvaPolar is […]
Whether you’re using them for next-level selfies or steady tracking shots, gimbals are a must for anyone who wants to maximize the potential of these powerful smartphone cameras we’re all carrying around. But those smartphones are also supposed to be portable, and let’s face it: Gimbals tend to offset that advantage. Weighing in at just […]
It’s too hot for yard sales, but hey: The internet is here for you. Here are the top ten deals on some of the Boing Boing Store’s best gear, just in time for summer. It’s everything from grills to security cameras to MacBook Pros, and they might be as low as they’re ever going to […]