In 1943 Sandoz chemist Albert Hofmann became the first person to synthesize (and take) LSD. He was also the first person to isolate and identify psilocybin, the main psychedelic component in magic mushrooms, almost 60 years ago. "Yet no one has been able to unravel the enzymatic pathway the mushrooms use to make psilocybin, until now," reports Stephen K. Ritter of Chemical and Engineering News.
Janis Fricke, Felix Blei, and Dirk Hoffmeister of Friedrich Schiller University Jena have identified and characterized to the greatest extent so far the four enzymes that the mushrooms use to make psilocybin. The team then developed the first enzymatic synthesis of the compound, setting the stage for its possible commercial production (Angew. Chem. Int. Ed. 2017, DOI: 10.1002/anie.201705489).
Image: Erik Fenderson/Wikipedia
The prohibition on psychedelics was memorably described as "the worst case of scientific censorship since the Catholic Church banned the works of Copernicus and Galileo" by former UK Drugs Czar David Nutt, and despite the ban, there has been a consistent, determined, very promising (sometimes surprising) drumbeat of scientific papers about the use of psilocybin […]
Salvia divinorum is a plant that is legal in most of the USA and the world, a uniquely powerful psychedelic whose effects are as short-lived (5-10 minutes from first onset to the end of the experience) as they are profound (users generally need to have a "sitter" nearby because they lose control over their bodies […]
The anonymous Bitcoin philanthropist behind the Pineapple Fund donated nearly 60 Bitcoins, approximately $1 million, to the psychedelics research and advocacy group Multidisciplinary Association for Psychedelic Studies (MAPS). “The Pineapple Fund’s outstanding generosity exemplifies how the growth of cryptocurrency can be leveraged for profound social change,” says MAPS Founder and Executive Director Rick Doblin, Ph.D. […]
Python is one of the most popular and versatile programming languages used by developers today, making it an ideal first choice for those looking to kickstart a career in programming. While you could go back to school or sign up for a pricey coding bootcamp, you can learn the essentials of coding with Python at […]
Going back to school isn’t necessarily an option for everyone. Between the time commitments and steep tuition rates, there are obstacles aplenty as far as furthering education is concerned. However, that’s not to say it’s impossible to learn new skills. Excel with Business lets users access thousands of hours of online learning in Microsoft, business, technology, […]
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