Biomedical engineers prototyped a pill that integrates a syringe to inject insulin into the floor of the stomach. From Science News:
The shape is designed to guide the device to rest, cap down, on the floor of the stomach. There, it sticks a needle tip composed almost entirely of insulin a few millimeters into the mucus membrane lining the stomach. Once the insulin needle tip dissolves, the device passes through the rest of the digestive system.
Thanks to the dearth of sharp pain receptors inside the stomach, the tiny injection “is unlikely to cause any discomfort,” says study coauthor Giovanni Traverso, a gastroenterologist and biomedical engineer at Brigham and Women’s Hospital in Boston and MIT.
"An ingestible self-orienting system for oral delivery of macromolecules" (Science)
From Deep Look: The quills of North American porcupines have microscopic backward-facing barbs on the tips. Those barbs make the quills slide in easy but very difficult to remove. Researchers at Harvard are looking to porcupine quills for inspiration in designing a new type of surgical staple that would also use tiny barbs to keep […]
In the UK, the routine vaccination of young girls has virtually eradicated new cases of cervical cancer associated with human papilomavirus. Researchers said the vaccine has nearly wiped out cases of cervical pre-cancer in young women since an immunisation programme was introduced 10 years ago. They found the vaccine had led to a 90% cut […]
The RaniPill is another syringe that you can swallow to deliver drugs to the bloodstream from the inside. It’s triggered by an interesting and complex mechanism involving a chemical reaction that inflates a tiny polymer balloon to push the needle into the intestinal wall. Rani Therapeutics just completed a successful 20-person trial using a pill […]
It’s 4/20! Smoke ’em if you got ’em – and if you haven’t got ’em, check out this roundup of deep discounts on pipes and other accessories. They’re all on sale, but you can take an extra discount off the final price courtesy of the Boing Boing store by using the online code 420SAVE. Freeze […]
Ever wonder if you’re cleaning your teeth well enough? If your last dentist visit has you getting a little more thorough about oral care, it might be time to save yourself some guesswork. A lot of electric toothbrushes promise deep cleaning, but there’s a Platinum Sonic Toothbrush that has power plus the simple but effective […]
The digital age is well and truly upon us, but let’s not forget there’s a load of free TV content floating literally over our heads. No, we’re not talking about the internet. Signals from major broadcast networks are still gratis for anyone who can pick them up with an antenna. And before you envision those […]