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WHO renames 2 Monkeypox "clades"

Photo: diy13 (Shutterstock)

The WHO announced that a "group of global experts convened by WHO" has:

agreed on new names for monkeypox virus variants, as part of ongoing efforts to align the names of the monkeypox disease, virus and variants—or clades—with current best practices. The experts agreed to name the clades using Roman numerals.

The monkeypox virus was named upon first discovery in 1958, before current best practices in naming diseases and viruses were adopted. Similarly for the name of the disease it causes. Major variants were identified by the geographic regions where they were known to circulate.

Current best practise is that newly-identified viruses, related disease, and virus variants should be given names with the aim to avoid causing offense to any cultural, social, national, regional, professional, or ethnic groups, and minimize any negative impact on trade, travel, tourism or animal welfare.

The WHO press release clarifies the new clade naming schema as:

The group reached consensus on new nomenclature for the virus clades that is in line with best practices. They agreed on how the virus clades should be recorded and classified on genome sequence repository sites.

Consensus was reached to now refer to the former Congo Basin (Central African) clade as Clade one (I) and the former West African clade as Clade two (II). Additionally, it was agreed that the Clade II consists of two subclades.

The proper naming structure will be represented by a Roman numeral for the clade and a lower-case alphanumeric character for the subclades. Thus, the new naming convention comprises Clade I, Clade IIa and Clade IIb, with the latter referring primarily to the group of variants largely circulating in the 2022 global outbreak. The naming of lineages will be as proposed by scientists as the outbreak evolves. Experts will be reconvened as needed.

The new names for the clades should go into effect immediately while work continues on the disease and virus names.

While the "Monkeypox" virus name change is still a work in progress at the International Committee on Taxonomy of Viruses (ICTV) and the WHO Family of International Health Related Classifications (WHO-FIC), as of this writing there are currently 14 proposed names before the ICTV & WHO-FIC:

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