In the Savvy Pscychologist, clinician Ellen Hendriksen of Boston University’s Center for Anxiety and Related Disorders, looks at the profound psychological and physiological impacts of feeling awe, whether it comes from looking up at the expansive night sky or hearing an incredible musical performance. She reflects on scientific evidence that awe makes us "feel small" and humble, nicer, and expands our worldview, all of which seem like fairly obvious effects. But Hendriksen also points to a recent curious study published in the journal Emotion showing that "awe is linked to decreased inflammation." The University of Toronto researchers had examined whether amusement, compassion, contentment, joy, love, pride, and awe resulted in "lower levels of a marker of inflammation called interleukin-6, or IL-6, which has been linked to diseases as diverse as rheumatoid arthritis, lupus, and diabetes." From the Savvy Psychologist:
Why on earth might standing on a mountaintop connect with our levels of inflammation? One hypothesis is that proinflammatory cytokines like IL-6 lead to physical and social withdrawal—curling up in your den and resting speeds recovery from illness or injury more quickly than pushing through. By contrast, awe triggers the opposite: an urge to explore and experience more. It’s unclear whether awe reduces inflammation or reduced inflammation makes us seek out awe, but either way, the two seem to be linked.
Here's the scientific study: "Positive affect and markers of inflammation: discrete positive emotions predict lower levels of inflammatory cytokines" (Emotion)