The comic book speculator market isn't normally the kind of cash cow that the 90s thought it was going to be. Unless you've got one of those very rare early superhero origin comics—or you happen to sell something random like Avengers #257 at the exact right time for a convenient movie tie-in—you're typically lucky to make even a dollar on an old comic.
Space Adventures #7 has nothing to do with superheroes, or non-superhero movie adaptations. But it's still coveted, probably because it contains a pre-Comics Code story called "Transformation" that was illustrated by Dick Giordano, who went on to become the Executive Editor at DC Comics, and written by a curiously uncredited author.
What's more interesting about the comic, however, is that it deals unexpectedly with transgender issues.
Here's a basic synopsis of the 8-page story from Comic Book Plus:
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Anticipating nuclear war that would leave Earth barren of life, Lars Kranston convinces his colleagues to go to Mars. His paramour Betty Stone insists that she go as well. The ship crashes on Mars. Everyone but Lars and Betty are killed, but Lars thinks she died too. Betty wakes up suffering total amnesia. Lars decides to use the supplies that survived the wreck. He manages a complete sex change. The tumultuous situation on Earth dies down. The predicted war never occurs. Betty remembers the journey.