Statins might make you a big jerk: unintended pharmacological side effects

Sounds like the clinical trials programs we use to approve drugs may have room to improve.

BBC:

He had diabetes, and he had signed up for a study to see if taking a “statin” – a kind of cholesterol-lowering drug – might help. So far, so normal.

But soon after he began the treatment, his wife began to notice a sinister transformation. A previously reasonable man, he became explosively angry and – out of nowhere – developed a tendency for road rage. During one memorable episode, he warned his family to keep away, lest he put them in hospital.

Out of fear of what might happen, Patient Five stopped driving. Even as a passenger, his outbursts often forced his wife to abandon their journeys and turn back. Afterwards, she’d leave him alone to watch TV and calm down. She became increasingly fearful for her own safety.

Then one day, Patient Five had an epiphany. “He was like, ‘Wow, it really seems that these problems started when I enrolled in this study’,” says Beatrice Golomb, who leads a research group at the University of California, San Diego.

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Arizona elementary school kids rushed to ER after popping pills

Apparently a 6-year-old got ahold of someone's prescription medication and decided to experiment with her friends.

Arizona's ABC15 reports:

According to Phoenix Fire Department, four elementary school students took "what appears to be heart medication pills" on the school bus Thursday morning.

Phoenix police say a 6-year-old girl took the prescription pills from an adult family member and gave them to four other 6- and 7-year-olds while they were on the way to school.

A staff member at the school became aware of what happened, brought the kids to the nurse's office, and called 911.

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