Not really, but Yale psychiatrist Marina Picciotto reports that targeting the brain receptors for nicotine could cut down the time it takes antidepressants like Prozac and Zoloft to begin working.
"In this study in mice, she and her colleagues tested the action of antidepressants with and without mecamylamine, a noncompetitive antagonist (blocker) in nicotinic acetylcholine receptors (nAChRs). In a separate study using knockout mice that lack these receptors, they found that the function of the nicotine receptor in the brain was an essential component of the therapeutic action of antidepressants."
