I haven't played a stringed instrument since high school, but "Captain Beefheart's 10 Commandments of Guitar Playing" sounds like damned good advice for whatever you're passionate about.
…2. Your guitar is not really a guitar
Your guitar is a divining rod. Use it to find spirits in the other world and bring them over. A guitar is also a fishing rod. If you're good, you'll land a big one.
3. Practice in front of a bush
Wait until the moon is out, then go outside, eat a multi-grained bread and play your guitar to a bush. If the bush doesn't shake, eat another piece of bread…
7. Always carry a church key
That's your key-man clause. Like One String Sam. He's one. He was a Detroit street musician who played in the fifties on a homemade instrument. His song "I Need a Hundred Dollars" is warm pie. Another key to the church is Hubert Sumlin, Howlin' Wolf's guitar player. He just stands there like the Statue of Liberty — making you want to look up her dress the whole time to see how he's doing it.
8. Don't wipe the sweat off your instrument
You need that stink on there. Then you have to get that stink onto your music.
(via Making Light)