Researchers at the US National Cancer Institute have reported in on an experimental breast cancer therapy that achieved remarkable results, rehabilitating Judy Perkins from the brink of death (she had been given two months to live, had tumors in her liver and throughout her body) to robust health two years later.
The therapy used the sequenced genome of the cancer to identify which elements of the cancer-cells might be "visible" to the patient's immune system; then the patient's white blood cells that were capable of targeting those traits were isolated and grown in vitro in huge numbers; finally, 90 billion of these cancer-targeting cells were injected back into the patient, along with drugs designed to "take the brakes off" the patient's immune system.
The team behind the therapy believe it may be applicable to other kinds of cancer.
These are the results from a single patient and much larger trials will be needed to confirm the findings.
The challenge so far in cancer immunotherapy is it tends to work spectacularly for some patients, but the majority do not benefit.
Dr Rosenberg added: "This is highly experimental and we're just learning how to do this, but potentially it is applicable to any cancer.
"At lot of works needs to be done, but the potential exists for a paradigm shift in cancer therapy - a unique drug for every cancer patient - it is very different to any other kind of treatment."
New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments [US National Cancer Institute/NIH]
'Remarkable' therapy beats terminal breast cancer [James Gallagher/BBC]
Yes, that is actually Space.com’s brilliant headline on this story about a new discovery from data collected in 1986 by NASA’s intrepid spacecraft. When the probe neared Uranus (heh heh), it measured the planet’s surrounding magnetic field. Recently, NASA scientists Gina DiBraccio and Daniel Gershman analyzing Voyager’s old data found a “wobble” in Uranus’s magnetosphere […]
Watch Quick test! from atinyworld on www.twitch.tv What the world needs now are tardigrades, sweet tardigrades. ‘A tiny world’ is a fun little internet window into the microscope with Julie Laurin, who lives in Ottowa, Ontario.
Cocaine, as they say, is one hell of a drug. In fact, it was recently shown in a study published in the Proceedings of the National Academy of Science to have greatly helped the re-wilding a good chunk of Columbia. How you might ask? Pablo Escobar’s hippos, which are still hanging around breeding in Columbia […]
At this point, it’s every single person’s responsibility to reduce their own carbon footprint and transition to a more sustainable lifestyle. But if you consider the grim fact that the biggest culprit of greenhouse gas emissions from human activities in the U.S. is burning fossil fuels for electricity, things, like pivoting to metal straws and […]
Companies that don’t have their own in-house design teams (which means 99 percent of all companies these days) face lots of serious questions. Among those questions is how you keep up with all the design requirements of a 21st-century company without the personnel. It isn’t just a website or an annual product catalog anymore. It’s […]
In case you’re one of those computer shoppers who instinctively turns up their nose at the very mention of the word refurbished, here are a couple myths worth dispelling. Refurbished equals junk somebody didn’t want. While desktops, laptops, notebooks, Chromebooks and tablets marked as refurbished may have been unboxed at some point, meaning they can […]