Researchers at the US National Cancer Institute have reported in on an experimental breast cancer therapy that achieved remarkable results, rehabilitating Judy Perkins from the brink of death (she had been given two months to live, had tumors in her liver and throughout her body) to robust health two years later.
The therapy used the sequenced genome of the cancer to identify which elements of the cancer-cells might be "visible" to the patient's immune system; then the patient's white blood cells that were capable of targeting those traits were isolated and grown in vitro in huge numbers; finally, 90 billion of these cancer-targeting cells were injected back into the patient, along with drugs designed to "take the brakes off" the patient's immune system.
The team behind the therapy believe it may be applicable to other kinds of cancer.
These are the results from a single patient and much larger trials will be needed to confirm the findings.
The challenge so far in cancer immunotherapy is it tends to work spectacularly for some patients, but the majority do not benefit.
Dr Rosenberg added: "This is highly experimental and we're just learning how to do this, but potentially it is applicable to any cancer.
"At lot of works needs to be done, but the potential exists for a paradigm shift in cancer therapy - a unique drug for every cancer patient - it is very different to any other kind of treatment."
New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments [US National Cancer Institute/NIH]
'Remarkable' therapy beats terminal breast cancer [James Gallagher/BBC]
Microplastics — the tiny pieces of plastic debris littering our planet — has been found in human poop, surprising nobody. The pilot study included 8 people from seven countries in Europe plus Japan. While the study was obviously very small, the researchers did discover waste plastic such as that from food wrappers and synthetic clothing […]
My name is Kelsey Juliana and I’m suing the United States government for causing and accelerating the climate change crisis. I’m 22 years old and I’ve been a climate advocate for more than half of my life.
Kevin M. Gill, a software engineer and data wrangler at NASA-JPL, created the fantastic video below “using still images taken by the Cassini spacecraft during it’s flyby of Jupiter and while at Saturn. “Shown is Io and Europa over Jupiter’s Great Red Spot and then Titan as it passes over Saturn and it’s edge-on rings,” […]
If you’re shopping for a camping lantern, you’re looking for reliability, period. So it’s nice to find something like the Revogi Convertible LED Lantern that jumps over that low bar and actually offers some versatility. Made of simple materials, the Revogi is high-tech in a refreshingly minimalist, eight-ounce package. Yes, it’ll light up the campsite […]
No matter what your business, Microsoft’s slate of Office software is as essential as desks and chairs – so much so that most workers are expected to know their way around it before they even get in the door. Whether you need an introduction, a brush-up or a level-up to your knowledge of these tools, […]
Speed reading isn’t just an innate skill possessed by a lucky few. Anyone can learn to speed read, and the benefits are endless. The brain can process more information than most people have time to soak up, but you can make that time now with the 2018 Award-Winning Speed Reading Bundle. The first half of […]