Researchers at the US National Cancer Institute have reported in on an experimental breast cancer therapy that achieved remarkable results, rehabilitating Judy Perkins from the brink of death (she had been given two months to live, had tumors in her liver and throughout her body) to robust health two years later.
The therapy used the sequenced genome of the cancer to identify which elements of the cancer-cells might be "visible" to the patient's immune system; then the patient's white blood cells that were capable of targeting those traits were isolated and grown in vitro in huge numbers; finally, 90 billion of these cancer-targeting cells were injected back into the patient, along with drugs designed to "take the brakes off" the patient's immune system.
The team behind the therapy believe it may be applicable to other kinds of cancer.
These are the results from a single patient and much larger trials will be needed to confirm the findings.
The challenge so far in cancer immunotherapy is it tends to work spectacularly for some patients, but the majority do not benefit.
Dr Rosenberg added: "This is highly experimental and we're just learning how to do this, but potentially it is applicable to any cancer.
"At lot of works needs to be done, but the potential exists for a paradigm shift in cancer therapy - a unique drug for every cancer patient - it is very different to any other kind of treatment."
New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments [US National Cancer Institute/NIH]
'Remarkable' therapy beats terminal breast cancer [James Gallagher/BBC]
NASA released this incredible image of the sky that depicts 22 months of X-ray data captured from the International Space Station using the Neutron star Interior Composition Explorer (NICER). From NASA: “Even with minimal processing, this image reveals the Cygnus Loop, a supernova remnant about 90 light-years across and thought to be 5,000 to 8,000 […]
In the realm of rocket geeks and space nerds, filmmakers MaryLiz Bender and Ryan Chylinski have dream jobs. The pair have the equivalent of “backstage passes” to SpaceX, NASA and ULA rocket launches where they capture and share breathtaking videos that convey the power, risk, and thrill of space exploration. The work of their studio, […]
The 1990s nanotechnology dream of tiny robots swimming through our blood stream to treat disease is moving (verrrry) slowly but surely toward reality. In a new milestone, researchers used an external magnetic field to steer microbots through a live mouse’s body carrying therapeutic stem cells. From IEEE Spectrum: ..Delivering stem cells typically requires an injection […]
Who needs a holiday sale? Sometimes there’s no better time than the thick of summer to find deals. We should know – we’ve found ten deep discounts on some must-have items. Whether you’re searching for CBD edibles, exercise gear, chargers or other tech, take a look. But don’t look long – these prices aren’t likely […]
Heading abroad? Even if it’s just a short trip, there’s a lot to prepare for. Travel can be incredibly rewarding, but it can tricky to navigate different cultures and lodging arrangements – and even trickier to do it cheaply. Before you go shopping for suitcases, here’s our pick for a good first investment: The Ultimate […]
Fried foods are a weakness for many of us. There’s nothing quite like that extra crisp crackle on chicken, fries or onion rings. And for years, our arteries have been paying for the privilege. Lately, the air fryer has been a godsend for those who love the fried stuff but love their body too. If […]