Russian scientist Denis Rebrikov claims that he's begun a gene-editing process to eventually enable couples who both carry a specific genetic mutation that causes deafness to birth children who can hear. Rebrikov formerly announced his effort to use the CRISPR tool for gene editing to create babies resistant to HIV. From Nature:
In his e-mail to Nature, Rebrikov makes clear that he does not plan to create (a gene-edited) baby yet — and that his previously reported plan to apply this month for permission to implant gene-edited embryos in women has been pushed back.
Instead, he says that he will soon publish the results of his egg experiments, which also involved testing CRISPR’s ability to repair the gene linked to deafness, called GJB2, in bodily cells taken from people with this mutation. People with two mutated copies of GJB2 cannot hear well without interventions, such as hearing aids or cochlear implants. Rebrikov says these results will lay the groundwork for the clinical work.
Rebrikov adds that he has permission from a local review board to do his research, but that this does not allow transfer of gene-edited eggs into the womb and subsequent pregnancy...
Some scientists and ethicists also call into question the benefits of this procedure because hearing loss is not a fatal condition. “The project is recklessly opportunistic, clearly unethical and damages the credibility of a technology that is intended to help, not harm,” says Jennifer Doudna, a pioneer of the CRISPR gene-editing tool and a biologist at the University of California, Berkeley.
This video depicts light speed in contexts where it appears to be slow. The moon is 1.2 light seconds from Earth; Mars several light minutes. This is, of course, why humans aren’t moving out of this solar system any time soon.
Randall Munroe's "Good Question" column in the New York Times is in the vein of his How To and What If books, in which he answers weird science questions with equally weird thoroughness.
This year’s episode of the grand meteor shower the Leonids will peak on Monday morning before dawn. The meteors are bits of debris dropping off the comet Tempel-Tuttle that intersects Earth’s orbit every November. Unfortunately, it may be tough to see many shooting stars because activity this year will be low and the waning gibbous […]
Need a boost on that resume? Get a valuable tech education on your own time with these eBook bundles. They contain guides from Packt Publishing that cover everything from game development to machine learning. The Complete Mobile App Developer eBook Bundle It’s a veritable gold rush in the App Store these days. Get in on […]
Vinyl is officially back. People are hearing the proof behind the initial “retro” excitement: that records really do have a richer sound. And if you haven’t switched to old-school records for serious listening, it’s a new golden age. Why? Because quality turntables like the Altec Lansing ALT-500 are finally available to a market other than […]
Between all of our apps, streaming devices, Bluetooth speakers, and energy-sucking decorations, paying for utilities each month can be…brutal. In fact, the average household spends roughly $70 a month on the water bill alone. That number might not seem terribly significant, but when you add it up, that’s $840 a year — a pretty significant […]