Princeton's David Tank just published a paper in Nature describing how he used the open-source Quake 2 engine to power a VR maze that he ran mice through in order to study their neurons while they moved. My wife, who played Quake on the British national team, wants to teach the mouse to rocket-jump.
Tank's team designed an apparatus in which a mouse, its head firmly held in a metal helmet, walks on the surface of a styrofoam ball. The ball is kept aloft by a jet of air, so that it functions like a multidirectional treadmill. Around it are sensors taken from optical computer mice, which read the ball's movement as the mouse runs.
Those readings were the input for the researchers' virtual reality software -- a modified version of the open source Quake 2 videogame engine, tweaked to project an image on a screen surrounding the mouse. Tank called it "a mini-IMAX theater."
Mice in the study ran through a virtual maze designed in the open source Quake game editor, but rather than earning points or power-ups, they were rewarded with sips of water from a head-side nozzle.
Into the hippocampus of each mouse the researchers inserted a glass capillary just one micron wide at its tip and filled with salt water. Known as a whole-cell patch recorder, it detects electrical currents as they pulse through individual cells.
"It is difficult to overstate the importance of understanding how the dynamics of electrical activity within single neurons is related to firing patterns among collections of neurons that accompany the performance of complex tasks," wrote Douglas Nitz, a University of California at San Diego cognitive scientist, in a commentary accompanying the findings.
With so many costumes adorning this election season, you might think the Halloween get-ups are overkill. Think again, because David Ng and B.R. Cohen are here to present the official universal survey about your candy favorites for the 2016 hierarchical delineation of candy virtue.
University of Zurich researchers used transcranial magnetic stimulation, a noninvasive method of inhibiting activity in parts of the brain, to “turn off” people’s ability to control their impulses. They focused on the temporoparietal junction, an area of the brain thought to play an important role in moral decisions, empathy, and other social interactions. They hope […]
Are you jonesing for a dose of optimism and possibility? In the mood to contemplate the cosmos? Want to experience a musical message for extraterrestrials the way it was meant to be played? The Voyager Golden Record: 40th Anniversary Edition, a project I launched with Timothy Daly and Lawrence Azerrad, is a lavish vinyl box […]
Geek Fuel is a subscription delivery service that caters to those of us that love comics, gaming, and general geek culture. Every month, Geek Fuel will assemble a box of goodies with a value of $50 or over. The specific items are a mystery, but you’ll always get an exclusive t-shirt not found anywhere else, a full […]
If you like to DIY and you like helicopters, you’re going to really love the Flexbot Hexacopter Kit. This copter blows traditional models out of the water: it includes everything you need to actually build your own hexacopter, and then pilot it like a pro, too.The construction is complicated enough to give you a challenge, […]
This week’s top deals from the Boing Boing Store range from lobster to wine to desk organization. 1. Get Maine Lobster (50% Off)With these discounted packages from Get Maine Lobster, you can experience the sweet, fresh flavor of world-renowned Maine lobster right at your own dinner table. There are four options to choose from, each at […]