Princeton's David Tank just published a paper in Nature describing how he used the open-source Quake 2 engine to power a VR maze that he ran mice through in order to study their neurons while they moved. My wife, who played Quake on the British national team, wants to teach the mouse to rocket-jump.
Tank's team designed an apparatus in which a mouse, its head firmly held in a metal helmet, walks on the surface of a styrofoam ball. The ball is kept aloft by a jet of air, so that it functions like a multidirectional treadmill. Around it are sensors taken from optical computer mice, which read the ball's movement as the mouse runs.
Those readings were the input for the researchers' virtual reality software -- a modified version of the open source Quake 2 videogame engine, tweaked to project an image on a screen surrounding the mouse. Tank called it "a mini-IMAX theater."
Mice in the study ran through a virtual maze designed in the open source Quake game editor, but rather than earning points or power-ups, they were rewarded with sips of water from a head-side nozzle.
Into the hippocampus of each mouse the researchers inserted a glass capillary just one micron wide at its tip and filled with salt water. Known as a whole-cell patch recorder, it detects electrical currents as they pulse through individual cells.
"It is difficult to overstate the importance of understanding how the dynamics of electrical activity within single neurons is related to firing patterns among collections of neurons that accompany the performance of complex tasks," wrote Douglas Nitz, a University of California at San Diego cognitive scientist, in a commentary accompanying the findings.
Princeton University psych prof Susan Fiske published an open letter denouncing the practice of using social media to call out statistical errors in psychology research, describing the people who do this as “terrorists” and arguing that this was toxic because of the structure of social science scholarship, having an outsized effect on careers.
Blue writes, “Peter Watts has be stricken with debilitating pain, loss of range of motion and motor control. Watts’ doctors remain baffled despite a battery of tests, and Watts has reached out to his fans to ask for their theories and ideas as to what might be causing his illness.”
Today, I’ve launched a very special Kickstarter with two friends, Timothy Daly and Lawrence Azerrad. A year in the making (and many more years on our minds), the Voyager Golden Record: 40th Anniversary Edition is the first vinyl release of the stunning golden phonograph record launched by NASA in 1977 aboard the Voyager spacecraft, one […]
If you own a dog, you’ve most likely heard of BarkBox – the monthly subscription box for dogs. What started as a simple idea to try out the subscription model on pet owners has since developed a cult following of dog lovers. If you haven’t given it a try yet, this one month free deal is the […]
With the iPhone headphone jack having gone by the wayside, we’re excited about the addition of the FRANKLIN Bluetooth Headphones in our store. These headphones are foldable so they’re easy to carry around, but most importantly, they pack impressive sound. Our biggest struggle with Bluetooth headphones is the worry of them dying at the worst moment. This pair lasts an impressive 8-10 […]
Evan Kimbrell, founder of the digital agency Sprintkick, recently released a series of online courses that feature some of the best advice we’ve come across. These courses are well worth your time, and will save you from making many typical mistakes down the line if you ever want to start your own business.With this Business […]