Because there are some things you can't ethically test on humans, human medical research involves animal models. Such models are useful and important. There is a lot we wouldn't know—and a lot of people whose lives would be much worse—if it weren't for these animals.
That said, animals models are not perfect. Especially when it comes to relatively subjective problems like mental health. We test anti-depressants on mice. But how do you know whether it's working? After all, the mouse can't tell you that it's feeling better. And you can't really watch what the mouse does and see behaviors directly relatable to the human experience of depression, either. (Does the mouse feel more like going to his job and interacting with his friends today?)
At Scientific American Mind, Robin Henig explains the three commonly used tests that give scientists a glimpse into the mouse psyche. These are flawed proxies. Given the very real questions about how effective anti-depressant drugs actually are, it's worth putting some effort into developing better ways of monitoring their effectiveness in animals. But, for now, this is what we have to go on.
Forced swimming test. The rat or mouse is placed into a cylinder partially filled with water from which escape is difficult. The longer it swims, the more actively it is trying to escape; if it stops swimming, this cessation is interpreted as depressionlike behavior, a kind of animal fatalism.
Find out about the other two tests at Scientific American Mind
Image: Mouse, a Creative Commons Attribution Share-Alike (2.0) image from iboy's photostream
The Cobham catalog, exposed by The Intercept, features countless pages of surveillance gadgets sold to U.S. police to spy on American citizens: tiny black boxes with a big interest in you. In the creepily bland feature lists and nerdy product names is a whisper of a dark future; perhaps darker than anyone can imagine.
This image depicts the most commonly-found stylesheet colors on the web’s top sites—Paul Hebert did an amazing amount of analysis and this is just one of the intriguing visualizations he came up with. Most of these are obvious staples, especially HTML red and blue, though it’s interesting how far the blue “cluster” is from the […]
With the cacophony of an election year ablaze with unparalleled drama being fought on the front lines of Twitter, we find ourselves slowing down and staring at it like a bad accident. The need for escapist relief is perhaps more dire than usual right now. This fall, if it’s drama you crave, but the Hillary […]
With the iPhone headphone jack having gone by the wayside, we’re excited about the addition of the FRANKLIN Bluetooth Headphones in our store. These headphones are foldable so they’re easy to carry around, but most importantly, they pack impressive sound. Our biggest struggle with Bluetooth headphones is the worry of them dying at the worst moment. This pair lasts an impressive 8-10 […]
Evan Kimbrell, founder of the digital agency Sprintkick, recently released a series of online courses that feature some of the best advice we’ve come across. These courses are well worth your time, and will save you from making many typical mistakes down the line if you ever want to start your own business.With this Business […]
Handy is the most convenient solution we’ve found for booking a house cleaning at the last minute, and they do a really great job. It’s as easy as heading to the site, selecting a date and time that works for you and the number of rooms in your home. We’ve even scheduled emergency cleanings as soon as the following day. […]