When the Combat Methamphetamine Epidemic Act of 2005 passed, pharmacies moved all cold-medicine with the actually-works ingredient pseudoephedrine, only available on request and with a copy of your ID. In its place, the pharmacy shelves were restocked with phenylephrine, which was alleged to work just as well. It doesn't work at all.
Researchers have long been suspicious of the efficacy of phenylephrine, but studies were mixed. Now, thanks to a University of Florida study published in The Journal of Allergy and Clinical Immunology: In Practice, whe know that phenylephrine is useless at the doses allowed over the counter; and may not work even at higher doses.
The study of 539 adults lasted one week and failed to find a dose of phenylephrine within the 10 mg to 40 mg range that was more effective than a placebo in relieving nasal congestion. The approved Food and Drug Administration (FDA) dose is 10 mg every four hours for “temporary relief of nasal congestion.”
Consequently, the UF researchers are asking the FDA to remove oral phenylephrine from the market.
“We think the evidence supports that phenylephrine’s status as a safe and effective over-the-counter product should be changed,” said Randy Hatton, Pharm.D., a clinical professor of pharmacotherapy and translational research. “We are looking out for the consumer, and he or she needs to know that science says that oral phenylephrine does not work for the majority of people.”
The Popular Over-The-Counter Cold Medicine That Science Says Doesn't Work [David DiSalvo/Forbes]
(Image: Sinuses, NIAID, CC-BY)
Yale scientists have managed to restore some biological function to the brains of dead pigs killed in a slaughterhouse 4 hours before the experiment.
Well, sort of. Paleontologists have identified a 430 million-year-old fossil of a multi-tentacled sea creature as a new species and dubbed it Sollasina cthulhu after HP Lovecraft’s Great Old One. From Yale University: The new cthulhu, Sollasina, had 45 tentacle-like tube feet, which it used to crawl along the ocean floor and capture food. The […]
Archaeologists uncovered the skeleton of this neolithic dog more than a century ago in a 5,000 year old tomb on on the island of Mainland, Orkney, Scotland. Now, forensic scientists and artists have reconstructed the animal’s face. According to Historic Environment Scotland researcher Steve Farrar, this dog and 23 others found in the “Cuween Hill […]
Believe it or not, PDF files have been the go-to format for contracts and forms of any type since 1993. And sure, they’re easily shareable – but that’s about it. When you need to edit or sign a document – and you will – that’s when frustration can set in. Luckily, there are workarounds, and […]
It’s 4/20! Smoke ’em if you got ’em – and if you haven’t got ’em, check out this roundup of deep discounts on pipes and other accessories. They’re all on sale, but you can take an extra discount off the final price courtesy of the Boing Boing store by using the online code 420SAVE. Freeze […]
Ever wonder if you’re cleaning your teeth well enough? If your last dentist visit has you getting a little more thorough about oral care, it might be time to save yourself some guesswork. A lot of electric toothbrushes promise deep cleaning, but there’s a Platinum Sonic Toothbrush that has power plus the simple but effective […]