A new molecular study shows that a compound called perrotetinene in certain species of liverworts is actually a psychoactive cannabanoid. From Science News:
A group of Japanese scientists in 1994 discovered perrotetinene in liverworts, but the new study is the strongest evidence yet that the compound is a psychoactive cannabinoid. Previously, cannabis was the only plant known to produce such cannabinoids….
After mapping perrotetinene's molecular structure, the researchers created a synthetic version and tested it on mice. The team tracked the animals' pain response, body temperature and movement — measures of the compound's psychoactivity. The results suggested that perrotetinene may be slightly less psychoactive than THC, says study coauthor Jürg Gertsch, a biochemist at the University of Bern in Switzerland. The liverwort compound may also have fewer negative side effects such as memory loss and loss of coordination, he says.
illustration: "Hepaticae" from Ernst Haeckel's Kunstformen der Natur, 1904