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Haters Gonna Hate: microscopic edition

Cory Doctorow at 10:53 am Sun, Jul 31, 2011

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Funniest captioning of a motor-protein ever. (after the jump, so I don't get lynched for a 2.5MB image on the front page) Haters gonna hate. [crosspost from r/gifs]

I write books. My latest is a YA science fiction novel called Homeland (it's the sequel to Little Brother). More books: Rapture of the Nerds (a novel, with Charlie Stross); With a Little Help (short stories); and The Great Big Beautiful Tomorrow (novella and nonfic). I speak all over the place and I tweet and tumble, too.

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  • Cowicide

    Look at that swagger!

    • professor

      I think I’d swagger too if my scrotum dragged along behind me like that!

  • bingobangoboy

    I don’t know if it’s the funniest ever, but I’d put it in the top 5.

  • Bucket

    Looks more R. Crumbesque to me.

    Keep on truckin, little protein.

  • Keith Moore

    From the Ministry of Silly Protein Walks.

  • Aceofblue

    Is it weird that I recognize the source video from a college biology course? It was a pretty great PBS special, I think.

    • Thiazi

      Yeah, it’s from the Inner Life of the Cell:

      http://www.youtube.com/watch?v=Mszlckmc4Hw

      It’s a few minutes long, and a visualization of molecular biology made by some folks at Harvard. It’s also nerdy awesomeness.

      • knoxblox

        *sigh*…Yes, nerdily awesome.

        It’s good that CG is utilized in this manner these days, but I sure wish the animation revolution had occurred before I was in school. I’m one of those people who had to SEE how it worked, and not just take some beeping filmstrip at its word.

  • http://www.facebook.com/graham.g.martin Graham Martin

    What is this?  I don’t even…

    • http://www.facebook.com/people/Robert-Sanders/100000011989161 Robert Sanders

      Just pretend you’re climbing up a rope while holding onto another rope, which is attached to a lever. That’s how a muscle would tighten to bend an arm.

  • http://twitter.com/bigbadchang Chang Terhune

    I tittered.

  • querent

    “Well you can tell by the way I use my walk….”

  • neurolux

    What is that? Actin?

    • FrancesTheMute

      That is the motor protein Kinesin “walking” along a microtubule carrying a storage vesicle(sack).  Microtubules are a part of the cells internal skeleton like actin but they form larger, hollow fibers out of the protein tubulin and they serve different roles.

    • http://twitter.com/AngerMonkey AngerMonkey

      That is probably dynein/dynactin walking along a microtubule. Or kinesin? I worked on tubulin (Drosphila beta3 in the hizzouse!) but I never could remember my motor proteins. Need to know about EMEF motif where they stick their little feets, though, and I’m your gal.

  • 9_9

    They see me rollin’
    They hatin’
    They trying to catch me walkin’ dirty (which I AAAAAAM)

  • http://www.facebook.com/people/John-Allen-Shaw/747996302 John Allen Shaw

    you know when a nerdy magazine uses the urban phrase “haters gonna hate”, it’s time to retire the phrase…

    • spejic

      I was using “haters gonna hate” before it was cool. Now I use “boop beep boop – droids”. You’ve probably never heard of it. I’ve only just put the sticker on my fixie.

      • haineux

        Have an artisinal bacon cupcake, “spejic”

  • ackpht

    And for those of us whose first language is English? 

  • http://disqus.com/Kimmoth/ Kimmo

    I knew microtubules were kind of like spokes in a spherical wheel, but I didn’t know they were tiny walkways for these groovy little jiggers!

    Awesome. Biology: fucking guaranteed to blow your mind.

  • futnuh

    The visualization was commissioned by Harvard. It was done by the folks at XVIVO, http://www.xvivo.net/.

  • http://pulse.yahoo.com/_BTXGTMKPAYOZSRIAPRSCB2LWIQ willam

    I buy that this is all accepted or well worked out science, but many many times in that video it seems like the voice over guy is just making shit up.