Haters Gonna Hate: microscopic edition

Funniest captioning of a motor-protein ever. (after the jump, so I don't get lynched for a 2.5MB image on the front page) Haters gonna hate. [crosspost from r/gifs]


  1. Is it weird that I recognize the source video from a college biology course? It was a pretty great PBS special, I think.

    1. Yeah, it’s from the Inner Life of the Cell:

      It’s a few minutes long, and a visualization of molecular biology made by some folks at Harvard. It’s also nerdy awesomeness.

      1. *sigh*…Yes, nerdily awesome.

        It’s good that CG is utilized in this manner these days, but I sure wish the animation revolution had occurred before I was in school. I’m one of those people who had to SEE how it worked, and not just take some beeping filmstrip at its word.

    1. Just pretend you’re climbing up a rope while holding onto another rope, which is attached to a lever. That’s how a muscle would tighten to bend an arm.

    1. That is the motor protein Kinesin “walking” along a microtubule carrying a storage vesicle(sack).  Microtubules are a part of the cells internal skeleton like actin but they form larger, hollow fibers out of the protein tubulin and they serve different roles.

    2. That is probably dynein/dynactin walking along a microtubule. Or kinesin? I worked on tubulin (Drosphila beta3 in the hizzouse!) but I never could remember my motor proteins. Need to know about EMEF motif where they stick their little feets, though, and I’m your gal.

  2. They see me rollin’
    They hatin’
    They trying to catch me walkin’ dirty (which I AAAAAAM)

    1. I was using “haters gonna hate” before it was cool. Now I use “boop beep boop – droids”. You’ve probably never heard of it. I’ve only just put the sticker on my fixie.

  3. I knew microtubules were kind of like spokes in a spherical wheel, but I didn’t know they were tiny walkways for these groovy little jiggers!

    Awesome. Biology: fucking guaranteed to blow your mind.

  4. I buy that this is all accepted or well worked out science, but many many times in that video it seems like the voice over guy is just making shit up. 

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