Last week, Shinya Yamanaka won a Nobel Prize for figuring out how to make adult stem cells revert to an embryonic (and much more medically useful) state. Within days, another scientist unconnected to Yamanaka, claimed to have produced such cells from human heart tissue and injected them back into human patients in a clinical trial. What's more, the researcher, Hisashi Moriguchi, claimed that a measure of his patients' heart function improved by 41.5% after the transplant.
It's hard to say which is crazier: The claims themselves, or the speed with which Moriguchi's story has completely fallen apart. Evidence suggests that these kind of re-programmed adult stem cells might be more likely to turn cancerous. Because of that, one of the first questions people asked was about the ethics committee that approved the research. Moriguchi said he worked for Harvard and that Harvard had signed off on his clinical trial.
And that's where things got nuts. Because Harvard had never heard of this study. And Moriguchi does not work there, anyway. In fact, this might not even be his field — the only professional affiliation that New Scientist could track down for him was as a visiting researcher in cosmetic surgery at The University of Tokyo. Also: The transplants may or may not have actually happened and Moriguchi might be plagiarizing images from other scientists. The worst part about this (from my perspective as a journalist) is that it was stem cell researchers who had to call out the fraud, after a major Japanese newspaper swallowed the story hook, line, and sinker.
New Scientist has a nice summary of this mess
You can follow the story much more in-depth at IPSCell.com, the blog of UC Davis stem cell researcher Paul Knoepfler.
Check out this post of Knoepfler's — written the day before the Moriguchi madness began — for more information on the risks of reprogrammed adult stem cells, the ongoing safety research, and proposed time-tables for when we will likely try these things out on humans for real.
It’s a commonplace that in the natural world, males attempt to mate with multiple females, while females attempt to entice males into being monogamous; this is attributed to the high cost of producing an egg and bearing children (or laying eggs) for females, and the low cost of sperm production for males.
Mathematician Stephen Wolfram and his company do a lot of consulting for Hollywood. But he doesn’t often do it on an urgent basis because a movie is about to shoot and they neglected to “tech the tech.” When I first started looking at the script for [Arrival], I quickly realized that to make coherent suggestions […]
Can you “hear” motion or light flashes? If so, according to new research from City University London, you may be experiencing a not-so-rare form of synaesthesia. Synesthesia is the fascinating neurological phenomenon whereby stimulation of one sense involuntarily triggers another sensory pathway. For example, a synesthete might taste sounds or hear colors. (In this study, […]
Whether I’m trying to relieve some stress at work or entertain myself on the metro, Space Putty is there. You can bring this magical goo home and try it for yourself for just $9.99Like Silly Putty of yesteryear, this viscoelastic substance can be molded into different shapes and stretched around in your hands. Use it […]
You know as well as I that writing complex, long-long form text requires significant organization. You’re probably also well aware that Word just isn’t up to the task. That’s why I’m a huge fan of Scrivener, the software suite used by best-selling authors and technical writers alike.Scrivener is much more than another digital typewriter. With a […]
Looking to upgrade your weekend? Here are three randomly awesome products on my mind this week.#3 FRESHeBUDS Pro Magnetic Bluetooth EarbudsAs more and more phones and gadgets switch to Bluetooth-only compatibility, you’ll need to get Bluetooth headphones like the rest of us. I’ve been super impressed with these affordable magnetic headphones. Pull the magnetic earbuds apart to auto-connect […]